2-(2-Bromo-4-methoxyphenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene CAS 2244085-55-8
| CAS No. | 2244085-55-8 |
| Molecular Formula | C14H8BrF5O2 |
| Molecular Weight | 383.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(2-Bromo-4-methoxyphenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(2-Bromo-4-methoxyphenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244085-55-8), a certified reference material (molecular formula C14H8BrF5O2, MW 383.11 g/mol) for analytical method development and quality control.
The molecular framework of 2-(2-Bromo-4-methoxyphenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (C14H8BrF5O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(2-Bromo-4-methoxyphenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H8BrF5O2 |
| Molecular Weight | 383.11 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 2-(4-Bromo-3-methoxyphenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244086-35-7)
- 2-(5-Bromo-2-methoxyphenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244083-07-4)
- n-(2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)pivalamide (CAS 1309980-68-4)
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Recommended Standards
- Bis(N-propylsalicylideneaminato)nickel (CAS 15379-66-5)
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- 4-Cyclopropyl-2-isopropylpyridin-3-amine (CAS 2397623-72-0)
- 1,2-Diphenyldisulfane (CAS 882-33-7)
- 5-(5-Methyl-thiophen-2-yl)-2H-pyrazole-3-carboxylic acid (CAS 1025010-00-7)
- 1-(4,5-Dibromothiophen-3-yl)ethanone (CAS 1823367-47-0)
- Mupirocin impurity 35 (CAS CATO-C4X-170635)
- N-Methyl-4-nitrobenzeneethanesulfonamide (CAS 98623-15-5)
- 2-(Aminomethyl)-6-(difluoromethyl)-5-iodopyridine-3-methanol (CAS 1805539-96-1)
- 2-(5-(4-Nitrophenyl)-1H-1,2,4-triazol-3-yl)acetonitrile (CAS 1255780-79-0)
- Insulin Degludec Impurity 15 (CAS CATO-C4X-215715)
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