1,3-Difluoro-2-(3-methyl-2-nitrophenoxy)-5-(trifluoromethyl)benzene CAS 2244088-75-1
| CAS No. | 2244088-75-1 |
| Molecular Formula | C14H8F5NO3 |
| Molecular Weight | 333.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1,3-Difluoro-2-(3-methyl-2-nitrophenoxy)-5-(trifluoromethyl)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1,3-Difluoro-2-(3-methyl-2-nitrophenoxy)-5-(trifluoromethyl)benzene (CAS 2244088-75-1), molecular formula C14H8F5NO3 and molecular weight 333.21 g/mol, is a CATO reference standard with documented purity and traceability.
1,3-Difluoro-2-(3-methyl-2-nitrophenoxy)-5-(trifluoromethyl)benzene (C14H8F5NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H8F5NO3 |
| Molecular Weight | 333.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 1,3-Difluoro-2-(2-methyl-3-nitrophenoxy)-5-(trifluoromethyl)benzene (CAS 2244083-49-4)
- 1,3-Difluoro-2-(4-methyl-2-nitrophenoxy)-5-(trifluoromethyl)benzene (CAS 2244086-55-1)
- 1-[2,6-difluoro-4-[2-(4-piperidyl)ethynyl]phenyl]hexahydropyrimidine-2,4-dione (CAS 2633725-40-1)
- 2,4-Difluoro-N-(2-((furan-2-ylmethyl)thio)ethyl)benzenesulfonamide (CAS 680211-96-5)
- 2,4-Difluoro-4-thiomorpholinomethyl benzophenone (CAS 898783-20-5)
- 3,4-Difluoro-2-thiomorpholinomethyl benzophenone (CAS 898782-44-0)
- 3,4-Difluoro-3-thiomorpholinomethyl benzophenone (CAS 898787-96-7)
- 3,5-Difluoro-2-thiomorpholinomethyl benzophenone (CAS 898782-47-3)
Recommended Standards
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- 1-(3,4-Dichlorophenyl)-4-(2-methoxyphenyl)-3-methyl-1H-pyrazole (CAS 956705-28-5)
- 4,6-Bis(4-chlorophenyl)-2-methyl-2,3,4,5-tetrahydropyridazin-3-one (CAS 866049-06-1)
- 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)ethanethioamide (CAS 172261-05-1)
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