tert-Butyl 6-bromo-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate CAS 2245084-41-5
| CAS No. | 2245084-41-5 |
| Molecular Formula | C18H22BrNO3 |
| Molecular Weight | 380.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
tert-Butyl 6-bromo-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate (CAS 2245084-41-5) is a high-purity analytical reference standard with the molecular formula C18H22BrNO3 and a molecular weight of 380.28 g/mol.
The molecular framework of tert-Butyl 6-bromo-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate (C18H22BrNO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), tert-Butyl 6-bromo-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H22BrNO3 |
| Molecular Weight | 380.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-Butyl 4-((2-bromophenyl)amino)-4-cyanopiperidine-1-carboxylate (CAS 205813-91-8)
- tert-butyl N-(5-bromopyrimidin-2-yl)-N-[(tert-butoxy)carbonyl]carbamate (CAS 209959-33-1)
- N1-(4-fluorophenyl)-2-(2-bromo-1-phenylethylidenE)-1-methylhydrazine-1-carbothioamide (CAS 680215-17-2)
- 2-(1H-Indol-3-yl)-2-oxo-N-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]acetamide (CAS 1024338-95-1)
- Cnx-1351 (CAS 1276105-89-5)
- 2,3-Dichloro-5-fluorobenzodifluoride (CAS 1803806-99-6)
- 1-((5-Chloro-4-propoxypyridin-3-yl)sulfonyl)piperazine (CAS 1352483-16-9)
- 3-(4-Chlorophenyl)-1H-1,2,4-triazole (CAS 23195-59-7)
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- 4-(3-Bromo-5-methylbenzyl)morpholine (CAS 1704073-29-9)
- Semaglutide Impurity 9 (CAS CATO-C4X-22269)
Why CATO?
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