Deucravacitinib Impurity 10 CAS 2245111-21-9
| CAS No. | 2245111-21-9 |
| Molecular Formula | C10H9ClN4O3 |
| Molecular Weight | 268.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Deucravacitinib Impurity 10 (CAS 2245111-21-9) is a certified pharmaceutical impurity reference standard with the molecular formula C10H9ClN4O3 and a molecular weight of 268.66 g/mol.
The molecular framework of Deucravacitinib Impurity 10 (C10H9ClN4O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9ClN4O3 |
| Molecular Weight | 268.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Deucravacitinib Standards
- Deucravacitinib Impurity 4 (CAS CATO-C4X-31384)
- Deucravacitinib Impurity 6 (CAS CATO-C4X-31386)
- Deucravacitinib Impurity 7 (CAS CATO-C4X-31387)
- Deucravacitinib Impurity 5 (CAS CATO-C4X-31385)
- Deucravacitinib Impurity 8 (CAS CATO-C4X-31388)
- Deucravacitinib Impurity 2 (CAS CATO-C4X-31382)
- Deucravacitinib Impurity 14 (CAS 1609394-23-1)
- Deucravacitinib Impurity 13 (CAS 2245111-18-4)
Recommended Standards
- Cenobamate Impurity 56 (CAS CATO-C4X-241656)
- ethyl (2Z)-3-[(2-chloro-4-fluorophenyl)amino]-2-cyanoprop-2-enoate (CAS 1181467-86-6)
- 503561-69-1 7-Chloro-4-nitro-5-(pyrrolidin-1-yl)-2,1,3-benzoxadiazole MFCD03269116 (CAS 503561-69-1)
- Ethyl 3-[(5-chloro-2-fluorophenyl)amino]-2-cyanoprop-2-enoate (CAS 1181482-69-8)
- Verapamil EP Impurity J HCl (CAS 67812-42-4)
- Fasudil Impurity 30 (CAS CATO-C4X-136530)
- Bupivacaine Impurity 30 (CAS 852804-30-9(free base))
- Alizarin Blue Black B (CAS 1324-21-6)
- 4-Chloro-5-(difluoromethyl)-2-iodopyridine-3-sulfonyl chloride (CAS 1804663-84-0)
- 2-(3-Fluorophenyl)-N-(pyridin-2-ylmethyl)ethan-1-amine (CAS 331970-64-0)
- 3,3-Difluoro-N-methoxy-N-methylcyclopentane-1-carboxamide (CAS 876757-20-9)
- 1-{5-[(1H-imidazol-1-yl)methyl]-1,3-thiazol-2-yl}-4-methylpiperazine (CAS 866137-05-5)
- 2-((4-Chlorophenethyl)thio)benzoic acid (CAS 1142202-47-8)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
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