1-(p-Tolyl)pyrimidine-2,4(1H,3H)-dione CAS 22455-92-1
| CAS No. | 22455-92-1 |
| Molecular Formula | C11H10N2O2 |
| Molecular Weight | 202.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(p-Tolyl)pyrimidine-2,4(1H,3H)-dione (CAS 22455-92-1) is a high-purity analytical reference standard with the molecular formula C11H10N2O2 and a molecular weight of 202.21 g/mol.
The molecular framework of 1-(p-Tolyl)pyrimidine-2,4(1H,3H)-dione (C11H10N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 1-(p-Tolyl)pyrimidine-2,4(1H,3H)-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10N2O2 |
| Molecular Weight | 202.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 2 |
Related p Standards
- 1-(p-Tolyl)pyrazine-2,3(1H,4H)-dione (CAS 1031605-84-1)
- 1-(p-Tolyl)-1H-pyrazole-4-carboxylic acid (CAS 1053085-48-5)
- 5-[1-o-Tolyl-meth-(Z)-ylidene]-imidazolidine-2,4-dione (CAS 115280-70-1)
- 6-(o-Tolyl)pyrimidine-2,4(1H,3H)-dione (CAS 1309609-29-7)
- 1-(P-tolyl)-1H-imidazole-4-carboxylic acid (CAS 14048-60-3)
- 1-(m-Tolyl)-1H-imidazole-4-carboxylic acid (CAS 952958-67-7)
- 3-(p-Tolyl)pyrimidine-2,4(1H,3H)-dione (CAS 4260-41-7)
- 5-(M-tolyl)furan-2-carboxylic acid (CAS 400744-57-2)
Recommended Standards
- 1-(pyridin-2-ylmethyl)-1H-pyrrole-2-carboxylic acid (CAS 896049-13-1)
- 1-(Furan-2-yl)-2-hydroxy-2-phenylethanone (CAS 36715-43-2)
- 1-(pyridin-3-ylmethyl)-1H-pyrrole-2-carboxylic acid (CAS 896049-17-5)
- 1-(Benzyloxy)-1H-imidazole-2-carbaldehyde (CAS 202211-96-9)
- 2-((5-(4-Chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(3-(furan-2-yl)allylidene)acetohydrazide (CAS 307975-51-5)
- Neon-<SUP>22</SUP>Ne (CAS 13886-72-1)
- Platinum,(2,2-dimethyl-1,3-propanediamine-N,N')[propanedioato(2-)-O,O']-,(SP-4-2) (CAS 72968-07-1)
- 1-Ethyl-1,2,3,4-tetrahydroquinoline-2-carbaldehyde (CAS 1707583-11-6)
- 2-(Biphenyl-2-yloxy)-propionic acid (CAS 119411-78-8)
- 2-[(4-chlorophenyl)sulfanyl]-5-fluorobenzoic acid (CAS 56096-90-3)
- 4-Chloropyridin-2-amine hydrochloride (CAS 202216-99-7)
- (2S,2’S)-1,1’-[(2-Hydroxy-5-methyl-1,3-phenylene)bis(methylene)]bis[alpha,alpha-diphenyl-2-pyrrolidinemethanol] (CAS 320714-00-9)
- 2-Ethoxy-5-nitropyrimidine-4-thiol (CAS 98141-07-2)
- Semaglutide Impurity 180 (CAS CATO-C4X-2226180)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com