4-Chloro-2-methoxy-5-nitroaniline CAS 22459-72-9
| CAS No. | 22459-72-9 |
| Molecular Formula | C7H7ClN2O3 |
| Molecular Weight | 202.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 202.60 g/mol gives 4-Chloro-2-methoxy-5-nitroaniline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Chloro-2-methoxy-5-nitroaniline (CAS 22459-72-9), molecular formula C7H7ClN2O3 and molecular weight 202.60 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 4-Chloro-2-methoxy-5-nitroaniline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 202.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Chloro-2-methoxy-5-nitroaniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H7ClN2O3 |
| Molecular Weight | 202.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 6-Chloro-2-ethoxy-3-nitropyridine (CAS 1094323-19-9)
- 2-Chloro-N,N-dimethyl-5-nitropyrimidin-4-amine (CAS 1131-14-2)
- 1-(2-Chloro-5-nitropyridin-4-yl)ethanol (CAS 1214241-89-0)
- Methyl 6-chloro-2-methoxypyrimidine-4-carboxylate (CAS 127840-06-6)
- Methyl 2-chloro-6-methoxypyrimidine-4-carboxylate (CAS 127861-30-7)
- 4-Chloro-2,6-dimethoxypyrimidine-5-carbaldehyde (CAS 134221-52-6)
- 2-Chloro-3-ethoxy-5-nitropyridine (CAS 1352910-89-4)
- 4-Chloro-6-ethyl-5-nitro-2-pyrimidinamine (CAS 1384431-00-8)
Recommended Standards
- 4,6-Dimethoxypyrimidine-2-carbonyl chloride (CAS 509101-33-1)
- 4-Chloro-2-methoxy-6-nitroaniline (CAS 859877-49-9)
- 3-Chloro-5-methoxy-2-nitroaniline (CAS 2091591-51-2)
- 4-Chloro-2-methyl-6,7-dihydro-[1,4]dioxino[2,3-c]pyridazin-3(2H)-one (CAS 863229-00-9)
- 4-Methoxy-2-vinylaniline (CAS 210536-47-3)
- 2-Chloro-1-[4-(2-hydroxyphenyl)piperazin-1-yl]propan-1-one (CAS 1178761-97-1)
- Pyrene-4,5-dione, 97% (CAS 6217-22-7)
- 4-Bromo-N,N-dipropylaniline (CAS 91935-18-1)
- Benzyl ((trans-4-hydroxypyrrolidin-3-yl)methyl)carbamate hydrochloride (CAS 1951444-34-0)
- (3-Bromo-2-butoxyphenyl)boronic acid (CAS 480425-34-1)
- (2Z)-4-(4-Ethoxyphenyl)-N-(4-fluorophenyl)-4-oxobut-2-enamide (CAS 331461-93-9)
- 2-(1-Aminopropyl)phenol (CAS 408350-84-5)
- (S)-Diethyl 2-aminopentanedioate (CAS 16450-41-2)
- Cholecystokinin Octapeptide free acid (desulfated) (H-2075.0001) (CAS 103974-46-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com