Pyridoxine Impurity 60 CAS 22464-27-3

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.22464-27-3
Molecular FormulaC8H12O2
Molecular Weight140.18 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Pyridoxine Impurity 60 CAS 22464-27-3 chemical structure

Description

As a process- or degradation-related impurity, Pyridoxine Impurity 60 (CAS 22464-27-3, C8H12O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Pyridoxine Impurity 60 (C8H12O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H12O2
Molecular Weight140.18 g/mol
Purity>95%
StorageStore at 2-8°C
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1963

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