6-Chloro-N-(2,4-difluorophenyl)pyridine-3-carboxamide CAS 224817-04-3
| CAS No. | 224817-04-3 |
| Molecular Formula | C12H7ClF2N2O |
| Molecular Weight | 268.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C12H7ClF2N2O, 6-Chloro-N-(2,4-difluorophenyl)pyridine-3-carboxamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 268.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
6-Chloro-N-(2,4-difluorophenyl)pyridine-3-carboxamide (CAS 224817-04-3) is a high-purity analytical reference standard with the molecular formula C12H7ClF2N2O and a molecular weight of 268.65 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H7ClF2N2O |
| Molecular Weight | 268.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2021 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 6-(5-Chloro-2-hydroxyphenyl)-2-oxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid (CAS 439095-04-2)
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- 4-Chloro-6-methoxy-1-methyl-3-nitroquinolin-2(1H)-one (CAS 2660228-77-1)
- ETHYL 2-(5-CHLORO-2-NITROPHENYL)-2-CYANOACETATE (CAS 62567-91-3)
- Ethyl (2Z)-2-chloro-2-[2-(3,5-dimethylphenyl)hydrazin-1-ylidene]acetate (CAS 154313-12-9)
- 1-Benzyl-5-methylpyrimidine-2,4(1H,3H)-dione (CAS 6306-73-6)
- 2-Propyl-2,3-dihydro-1h-isoindol-4-amine (CAS 1099677-96-9)
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