Risdiplam Impurity 8 CAS 2250441-24-6
| CAS No. | 2250441-24-6 |
| Molecular Formula | C22H23N7O2 |
| Molecular Weight | 417.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Risdiplam Impurity 8 (CAS 2250441-24-6), a pharmacopoeial impurity reference standard (molecular formula C22H23N7O2, MW 417.46 g/mol) used for the identification and quantification of trace impurities in APIs.
Risdiplam Impurity 8 (C22H23N7O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Risdiplam Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H23N7O2 |
| Molecular Weight | 417.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 7 |
Related Risdiplam Standards
- Risdiplam impurity 7 (CAS CATO-C4X-30127)
- Risdiplam Impurity 3 (CAS CATO-C4X-30123)
- Risdiplam Impurity 4 (CAS CATO-C4X-30124)
- Risdiplam Impurity 1 (CAS CATO-C4X-30121)
- Risdiplam impurity 5 (CAS CATO-C4X-30125)
- Risdiplam (CAS 1825352-65-5)
- Risdiplam Impurity 9 (CAS CATO-C4X-30129)
- Risdiplam impurity 11 (CAS CATO-C4X-301211)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com