3-Chloro-2,6-difluorobenzoic acid CAS 225104-76-7
| CAS No. | 225104-76-7 |
| Molecular Formula | C7H3ClF2O2 |
| Molecular Weight | 192.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-Chloro-2,6-difluorobenzoic acid (CAS 225104-76-7), a certified reference material (molecular formula C7H3ClF2O2, MW 192.55 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 3-Chloro-2,6-difluorobenzoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 192.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Chloro-2,6-difluorobenzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H3ClF2O2 |
| Molecular Weight | 192.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2021 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-4,5-difluorobenzoic acid (CAS 110877-64-0)
- 4-Chloro-3,5-difluorobenzoic Acid (CAS 1160573-19-2)
- 5-Chloro-2,3-difluorobenzoic acid (CAS 1227270-64-5)
- 2-Chloro-4,6-difluorobenzoic acid (CAS 1242339-67-8)
- 3-Chloro-2,5-difluorobenzoic acid (CAS 1261629-01-9)
- 5-Chloro-2,4-difluorobenzoic Acid (CAS 130025-33-1)
- 4-Chloro-2,5-difluorobenzoic acid; (CAS 132794-07-1)
- 2-Chloro-3,4-difluorobenzoic Acid (CAS 150444-93-2)
Recommended Standards
- 3,4-Difluorophenyl chloroformate (CAS 841258-01-3)
- 4-Chloro-2,3-difluoro-5-hydroxybenzaldehyde (CAS 2056110-34-8)
- 2-Chloro-3,6-difluorobenzoic Acid (CAS 287172-74-1)
- 5-Chloro-2,2-difluoro-1,3-benzodioxole (CAS 72769-08-5)
- 3-Fluoro-4-(piperidin-1-ylamino)nitrobenzene (CAS 1549292-52-5)
- 4-(4-methyl-1,3-oxazol-5-yl)aniline (CAS 267648-20-4)
- Ethyl Sulfide (CAS 352-93-2)
- N-(2-(tert-butylthio)ethyl)-4-chlorobenzenesulfonamide (CAS 666699-37-2)
- 2-(4-(Difluoromethyl)-6-fluoro-5-methylpyridin-2-yl)acetic acid (CAS 1805617-90-6)
- 1-(Cyclopropanecarbonyl)azetidine-3-carboxylic acid (CAS 1341284-50-1)
- (Cyclopentylmethyl)[(2,5-difluorophenyl)methyl]amine (CAS 1096788-56-5)
- (S)-5-(tert-butoxycarbonyl)-4-oxo-5-azaspiro[2.4]Heptane-6-carboxylic acid (CAS 2306253-69-8)
- 2-Amino-3-chloro-5-fluoropyridine (CAS 1214330-79-6)
- Palmitoyl Tripeptide-1 HCl (CAS 2757690-14-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com