1-(4-Fluorophenyl)piperazine CAS 2252-63-3
| CAS No. | 2252-63-3 |
| Molecular Formula | C10H13FN2 |
| Molecular Weight | 180.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Fluorophenyl)piperazine.
1-(4-Fluorophenyl)piperazine (CAS 2252-63-3) is a high-purity analytical reference standard with the molecular formula C10H13FN2 and a molecular weight of 180.22 g/mol.
1-(4-Fluorophenyl)piperazine (C10H13FN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(4-Fluorophenyl)piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H13FN2 |
| Molecular Weight | 180.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- 3-(4-fluorophenyl)-3-methylbutan-2-one (CAS 1017409-06-1)
- 1-(2-Fluorophenyl)pyrrolidin-3-amine (CAS 1096836-33-7)
- 1-(3-Fluorophenyl)pentan-2-one (CAS 1176544-30-1)
- 1-(3-Fluorophenyl)-3-methylbutan-2-one (CAS 1178714-08-3)
- 2-(4-Fluorophenyl)-3-methylbutanal (CAS 1181631-88-8)
- 1-(3-Fluorophenyl)-3-methylbutan-1-one (CAS 1183881-59-5)
- (R)-2-(4-Fluorophenyl)piperazine (CAS 1213496-32-2)
- (R)-2-(2-Fluorophenyl)piperazine (CAS 1213908-28-1)
Recommended Standards
- 1-(4-Fluorophenyl)pentan-3-one (CAS 63416-75-1)
- 1-(4-Fluorophenyl)pyrrolidin-3-amine (CAS 859164-73-1)
- 1-(4-Fluorophenyl)pent-4-en-1-ol (CAS 85494-43-5)
- 1-(5-Fluoropyridin-3-yl)cyclopentan-1-amine (CAS 944142-76-1)
- (2-carboxy-3-hydroxy-3-methylbutan-2-yl)oxy-(1H-indol-2-yl)boron 476004-81-6 A827280 [2,3-dimethyl-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]oxy-(1H-indol-2-yl)boron (CAS 476004-81-6)
- Antibiotic LL Z1640-4 (CAS 66018-41-5)
- Methyl 5-N,4-O-Carbonyl-3,5-dideoxy-2-S-phenyl-2-thio-D-glycero-β-D-galacto-2-nonulopyranosylonate (CAS 934591-79-4)
- 2-Ethyl-N-(1-methoxypropan-2-yl)aniline (CAS 51218-94-1)
- n-(6-(Dimethylamino)pyridin-3-yl)butyramide (CAS 1007651-99-1)
- (R)-2-phenethylpyrrolidine-2-carboxylic acid hydrochloride (CAS 1217684-31-5)
- Itaconic Acid (CAS 97-65-4)
- 5-bromo-1-methyl-1,2,3,6-tetrahydropyridine (CAS 365261-27-4)
- 2-Amino-1-(3-iodophenyl)-4,5-dimethyl-1H-pyrrole-3-carbonitrile (CAS 1152656-16-0)
- Acetyl Hexapeptide-38 (CAS 1400634-44-7)
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