2-(Hydroxy(2-nitrophenyl)methyl)acrylonitrile CAS 225237-20-7
| CAS No. | 225237-20-7 |
| Molecular Formula | C10H8N2O3 |
| Molecular Weight | 204.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(Hydroxy(2-nitrophenyl)methyl)acrylonitrile (CAS 225237-20-7), molecular formula C10H8N2O3 and molecular weight 204.18 g/mol, is a CATO reference standard with documented purity and traceability.
2-(Hydroxy(2-nitrophenyl)methyl)acrylonitrile (C10H8N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 2-(Hydroxy(2-nitrophenyl)methyl)acrylonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O3 |
| Molecular Weight | 204.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2021 |
| Nitrogen Atoms | 2 |
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- 6-(2-Aminophenyl)-3-methyl-7H-thiazolo[3,2-b][1,2,4]triazin-7-one (CAS 491581-72-7)
- Fenoterol Impurity 4 (CAS 161040-25-1)
- 5-Methoxy-4-methyl-2-nitrobenzoic acid (CAS 857599-32-7)
- 2-((Cyanomethyl)thio)-N-isobutylbenzamide (CAS 1181490-17-4)
- 3-Methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridine-8-carboxylic acid (CAS 1190392-06-3)
- 1-((4-(Tert-butyl)phenyl)sulfonyl)-6-methyl-1,2,3,4-tetrahydroquinoline (CAS 562079-21-4)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
Why CATO?
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