4-Bromo-1-(trifluoromethyl)-1H-imidazole CAS 2253632-50-5
| CAS No. | 2253632-50-5 |
| Molecular Formula | C4H2BrF3N2 |
| Molecular Weight | 214.97 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Bromo-1-(trifluoromethyl)-1H-imidazole.
CATO supplies 4-Bromo-1-(trifluoromethyl)-1H-imidazole (CAS 2253632-50-5), a certified reference material (molecular formula C4H2BrF3N2, MW 214.97 g/mol) for analytical method development and quality control.
4-Bromo-1-(trifluoromethyl)-1H-imidazole (C4H2BrF3N2) contains a nitrile group, fluorine/bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H2BrF3N2 |
| Molecular Weight | 214.97 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 4-Bromo-1-(trifluoromethyl)-1H-pyrazole (CAS 1046831-97-3)
- 2-Bromo-5-(trifluoromethyl)furan (CAS 1289005-52-2)
- 3-Bromo-4-(trifluoromethyl)-1H-pyrazole (CAS 1936710-01-8)
- 2-Bromo-5-(trifluoromethyl)-1H-imidazole (CAS 219535-00-9)
- 3-Bromo-1-(trifluoromethyl)-1H-pyrazole (CAS 2092804-01-6)
- 3-Bromo-5-(trifluoromethyl)pyrazole (CAS 93608-11-8)
- 4-Bromo-3-(trifluoromethyl)pyrazole (CAS 19968-17-3)
- 4-Bromo-5-(trifluoromethyl)-1H-pyrazole (CAS 918339-68-1)
Recommended Standards
- 5-Bromo-1-(trifluoromethyl)-1H-pyrazole (CAS 2092678-45-8)
- (2-Fluoro-6-(2-methoxyethoxy)pyridin-3-yl)boronic acid (CAS 1253575-61-9)
- Allyl bromodifluoroacetate (CAS 155820-76-1)
- 1-Bromo-1,1-difluoropentane-2,4-dione (CAS 164342-73-8)
- 6-Chloro-5-methylnicotinic acid (CAS 66909-29-3)
- 6-(3-Chlorophenyl)-2-hydroxy-4-(trifluoromethyl)nicotinonitrile (CAS 338749-71-6)
- 5,8-Difluoro-4,4-dimethyl-3,4-dihydro-2H-[1,3'-biquinolin]-2-one (CAS 918646-24-9)
- Cephacetrile (CAS 10206-21-0)
- Methyl 3-amino-3-(3,4-difluorophenyl)propanoate (CAS 1038338-73-6)
- Ethyl 7-hydroxy-6-methyl-1H-pyrrolo[3,4-c]pyridine-2(3H)-carboxylate (CAS 806645-88-5)
- 2-(Hydroxymethyl)-4,5-dimethylphenol (CAS 10496-92-1)
- N-Octylacridin-9-amine (CAS 111782-80-0)
- 1,4,5,8-Tetraamino-2,7-bis(3-butoxypropoxy)anthracene-9,10-dione (CAS 88601-75-6)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
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