2-(Hydroxymethyl)-5-nitroisoindoline-1,3-dione CAS 22546-83-4
| CAS No. | 22546-83-4 |
| Molecular Formula | C9H6N2O5 |
| Molecular Weight | 222.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(Hydroxymethyl)-5-nitroisoindoline-1,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-(Hydroxymethyl)-5-nitroisoindoline-1,3-dione (CAS 22546-83-4), a certified reference material (molecular formula C9H6N2O5, MW 222.15 g/mol) for analytical method development and quality control.
2-(Hydroxymethyl)-5-nitroisoindoline-1,3-dione (C9H6N2O5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6N2O5 |
| Molecular Weight | 222.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 2 |
Related Hydroxymethyl Standards
- (R)-6-(Hydroxymethyl)-1-(4-hydroxyphenyl)piperazin-2-one (CAS 1217608-77-9)
- 2-[2-(hydroxymethyl)pyrrolidin-1-yl]pyridine-4-carboxylic acid (CAS 1247361-28-9)
- 2-(2-(Hydroxymethyl)pyrrolidin-1-yl)nicotinic acid (CAS 1251145-95-5)
- 4,4-Bis(hydroxymethyl)-1-phenylpyrazolidin-3-one (CAS 13047-10-4)
- 5-(Hydroxymethyl)-3-phenyl-2-thioxoimidazolidin-4-one (CAS 5789-22-0)
- N-(4-(hydroxymethyl)cyclohexyl)ethanesulfonamide (CAS 1863674-15-0)
- 3-((2-(Hydroxymethyl)-2-methylbutyl)amino)thietane 1,1-dioxide (CAS 1866496-64-1)
- 4-Benzyl-2-(hydroxymethyl)homomorpholine (CAS 1031442-66-6)
Recommended Standards
- 1-Methyl-6-nitro-2,4-dihydro-1h-3,1-benzoxazine-2,4-dione (CAS 4693-01-0)
- 2,3,5,8-Tetrahydroxynaphthalene-1,4-dione (CAS 476-54-0)
- 1,3-dichloro-6-methyl-isoquinoline (CAS 21902-38-5)
- 2-bromothieno[3,2-b]pyridine (CAS 94191-15-8)
- 3-fluorocyclopentanamine (CAS 1393527-84-8)
- eseridine (CAS 25573-43-7)
- Ethyl 2-(1,4-diazepan-1-yl)acetate (CAS 913645-28-0)
- 5-(Trifluoromethyl)isoquinolin-1-ol (CAS 630423-22-2)
- 8-(3-(3',6'-DIhydroxy-3-oxo-3h-spiro[isobenzofuran-1,9'-xanthen]-5-yl)thioureido)octanoic acid (CAS 171263-01-7)
- C26-Dihydro Ceramide (CAS 182362-38-5)
- 2-Bromo-5-cyclopropoxypyrazine (CAS 1209458-65-0)
- Cyclopropyl-(5-isopropylpyridin-2-yl)-amine (CAS 1093955-11-3)
- 5,5-Dimethyl-3,4,5,6-tetrahydropyridin-2-amine hydrochloride (CAS 179684-15-2)
- Gastric Inhibitory Polypeptide (1-30) amide (porcine) (CAS 134846-93-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com