2-(Methylthio)acetamide CAS 22551-24-2
| CAS No. | 22551-24-2 |
| Molecular Formula | C3H7NOS |
| Molecular Weight | 105.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Methylthio)acetamide.
2-(Methylthio)acetamide (CAS 22551-24-2) is a high-purity analytical reference standard with the molecular formula C3H7NOS and a molecular weight of 105.16 g/mol.
The molecular framework of 2-(Methylthio)acetamide (C3H7NOS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(Methylthio)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C3H7NOS |
| Molecular Weight | 105.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Methylthio Standards
- (2S)-1-(Methylthio)propan-2-amine DISCONTINUED, offer M725614 (CAS 741658-04-8)
- (R)-1-(methylthio)propan-2-amine (CAS 927663-50-1)
- 2-(Methylthio)acetic acid (CAS 2444-37-3)
- 2-(Methylthio)acetimidamide (CAS 105324-23-0)
- 1-(Methylthio)propan-2-one (CAS 14109-72-9)
- 3-(Methylthio)propionaldehyde (CAS 3268-49-3)
- 3-(Methylthio)azetidine (CAS 742670-23-1)
- Bis(methylthio)methane (CAS 1618-26-4)
Recommended Standards
- 1,2,5-thiadiazol-3-amine (CAS 6504-55-8)
- 2-Mercapto-N-methylacetamide (CAS 20938-74-3)
- 1,2,4-thiadiazol-3-amine (CAS 56531-89-6)
- 3-Mercaptopropanamide (CAS 763-35-9)
- 3-Hydroxy-5-(4-isopropylphenyl)-1-(5-methyl-1,3,4-thiadiazol-2-yl)-4-(4-methylbenzoyl)-1H-pyrrol-2(5H)-one (CAS 609794-25-4)
- N-(2-(Dimethylamino)ethyl)-9-phenoxyacridine-4-carboxamide (CAS 89459-24-5)
- 2-(2,4,7-Trimethyl-1H-indol-3-yl)acetic acid (CAS 5435-43-8)
- 4-[(4-Benzylphenoxy)methyl]piperidine (CAS 883510-80-3)
- Tert-butyl (3-(aminomethyl)-4,4,4-trifluorobutyl)carbamate (CAS 1354952-06-9)
- 4-Aminobenzyl butyrate (CAS 46347-99-3)
- 4-({[(1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)methyl]amino}methyl)benzoic acid (CAS 1022362-21-5)
- (S)-Methyl 2-(pyrrolidin-2-yl)-1H-benzo[d]imidazole-5-carboxylate dihydrochloride (CAS 1439922-01-6)
- 4-(4-Chlorobenzyl)tetrahydro-2h-thiopyran-4-carboxylic acid 1,1-dioxide (CAS 2197052-50-7)
- Prolactin-Releasing Peptide (12-31) (human) (CAS 235433-36-0)
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