Ethyl 2-chloropyrrolo[2,1-f][1,2,4]triazine-4-carboxylate CAS 2255366-50-6
| CAS No. | 2255366-50-6 |
| Molecular Formula | C9H8ClN3O2 |
| Molecular Weight | 225.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 2-chloropyrrolo[2,1-f][1,2,4]triazine-4-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Ethyl 2-chloropyrrolo[2,1-f][1,2,4]triazine-4-carboxylate (CAS 2255366-50-6), a certified reference material (molecular formula C9H8ClN3O2, MW 225.63 g/mol) for analytical method development and quality control.
The molecular framework of Ethyl 2-chloropyrrolo[2,1-f][1,2,4]triazine-4-carboxylate (C9H8ClN3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H8ClN3O2 |
| Molecular Weight | 225.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- Ethyl 4-chloropyrrolo[2,1-f][1,2,4]triazine-2-carboxylate (CAS 1120214-92-7)
- Ethyl 4-chloropyrrolo[2,1-f][1,2,4]triazine-7-carboxylate (CAS 1356016-43-7)
- Ethyl 4-chloropyrrolo[2,1-f][1,2,4]triazine-5-carboxylate (CAS 1408064-98-1)
- Ethyl 4-Chloropyrrolo[2,1-f][1,2,4]triazine-6-carboxylate (CAS 903129-94-2)
- Ethyl 4-chloropyrrolo[1,2-b]pyridazine-3-carboxylate (CAS 1400688-74-5)
- Ethyl 6-Chloropyrrolo[2,3-b]pyridine-2-carboxylate (CAS 287384-84-3)
- 3-{4-chloropyrrolo[2,1-f][1,2,4]triazin-7-yl}-2-methylpropanenitrile (CAS 2091356-76-0)
- 3-{4-chloropyrrolo[2,1-f][1,2,4]triazin-7-yl}butanenitrile (CAS 2092669-99-1)
Recommended Standards
- Ethyl 2-chloroimidazo[1,2-b]pyridazine-7-carboxylate (CAS 2577171-68-5)
- Ethyl 3-chloro-1H-pyrazolo[3,4-c]pyridine-5-carboxylate (CAS 2089377-67-1)
- Ethyl 2-chloro-5H-pyrrolo[3,2-d]pyrimidine-6-carboxylate (CAS 2089378-36-7)
- Ethyl 3-chloroimidazo[1,2-a]pyrimidine-2-carboxylate (CAS 860612-52-8)
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