Tert-butyl 4-(4-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine-1-carboxylate CAS 2256708-69-5
| CAS No. | 2256708-69-5 |
| Molecular Formula | C22H33BFNO4 |
| Molecular Weight | 405.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Tert-butyl 4-(4-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine-1-carboxylate (CAS 2256708-69-5), a certified reference material (molecular formula C22H33BFNO4, MW 405.31 g/mol) for analytical method development and quality control.
The molecular framework of Tert-butyl 4-(4-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine-1-carboxylate (C22H33BFNO4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H33BFNO4 |
| Molecular Weight | 405.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-Butyl 4-(3-bromophenylsulfonyl)piperazine-1-carboxylate (CAS 937014-80-7)
- 1-(3,4-dichlorobenzyl)-3-methyl-4-pivaloyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 1009248-84-3)
- Tert-butyl 4-((4-bromophenyl)sulfonyl)piperazine-1-carboxylate (CAS 259808-63-4)
- 6-(5,6-Difluoro-2-methyl-1H-benzo[d]imidazol-1-yl)-N-(4-(trifluoromethyl)phenyl)pyrazin-2-amine (CAS 1782970-28-8)
- n-Allyl-2-((2,4-dimethylphenyl)amino)propanamide (CAS 1132788-62-5)
- Sodium (2R,3S,4R,5R)-2,3,4,5-tetrahydroxy-6-(phosphonatooxy)hexanoate dihydrate (CAS 57775-17-4)
- 1-(3,4-Difluorophenyl)-2-methoxyethan-1-amine (CAS 954253-20-4)
- 2-Acetamido-5-aminobenzoic acid (CAS 54669-98-6)
- 2-Amino-4,5-dihydrothiophene-3-carboxamide (CAS 133036-77-8)
- tert-Butyl N-[(1S,2R)-rel-2-(6-bromopyridin-3-yl)cyclopropyl]carbamate (CAS 918305-73-4)
- (S)-Benzyl (3-hydroxy-1-(methylamino)-1-oxopropan-2-yl)carbamate (CAS 19647-68-8)
- 2-(Aminomethyl)-6-bromo-5-(difluoromethyl)pyridine-3-acetic acid (CAS 1804845-76-8)
- 4-(2,2-Diethoxyethoxy)benzonitrile (CAS 787575-81-9)
- GnRH Associated Peptide (GAP) (1-13), human (CAS 100111-07-7)
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