(4-(Piperidin-3-yl)-3-(trifluoromethyl)phenyl)boronic acid CAS 2256708-80-0
| CAS No. | 2256708-80-0 |
| Molecular Formula | C12H15BF3NO2 |
| Molecular Weight | 273.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(4-(Piperidin-3-yl)-3-(trifluoromethyl)phenyl)boronic acid (CAS 2256708-80-0) is a high-purity analytical reference standard with the molecular formula C12H15BF3NO2 and a molecular weight of 273.06 g/mol.
The molecular framework of (4-(Piperidin-3-yl)-3-(trifluoromethyl)phenyl)boronic acid (C12H15BF3NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (4-(Piperidin-3-yl)-3-(trifluoromethyl)phenyl)boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H15BF3NO2 |
| Molecular Weight | 273.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Piperidin Standards
- (3-(Piperidin-1-yl)-4-(trifluoromethyl)phenyl)boronic acid (CAS 1187874-86-7)
- (2-(Piperidin-3-yl)-4-(trifluoromethyl)phenyl)boronic acid (CAS 2225151-82-4)
- (3-(Piperidin-3-yl)-5-(trifluoromethyl)phenyl)boronic acid (CAS 2225152-66-7)
- (3-(Piperidin-4-yl)-4-(trifluoromethyl)phenyl)boronic acid (CAS 2225155-40-6)
- (3-(Piperidin-4-yl)-5-(trifluoromethyl)phenyl)boronic acid (CAS 2225170-15-8)
- (4-(Piperidin-1-yl)-2-(trifluoromethyl)phenyl)boronic acid (CAS 2225179-13-3)
- (4-(Piperidin-4-yl)-3-(trifluoromethyl)phenyl)boronic acid (CAS 2225169-45-7)
- (5-(Piperidin-3-yl)-2-(trifluoromethyl)phenyl)boronic acid (CAS 2225152-80-5)
Recommended Standards
- (5-(Piperidin-4-yl)-2-(trifluoromethyl)phenyl)boronic acid (CAS 2225171-95-7)
- (5-Cyclohexyl-6-(trifluoromethyl)pyridin-3-yl)boronic acid (CAS 2225180-49-2)
- 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine (CAS 881402-16-0)
- Methyl 2-amino-4-bromo-3-cyano-5-fluorobenzoate (CAS 1878218-27-9)
- Tert-butyl (R)-2-(5-bromo-1H-imidazol-2-yl)-2-methylpyrrolidine-1-carboxylate (CAS 2227198-16-3)
- (2-Cyclopropyl-5-(methoxycarbonyl)phenyl)boronic acid (CAS 2225169-37-7)
- 1,2,3-Trivinylbenzene (CAS 1322-23-2)
- Sertraline Impurity 50 HCl (CAS 122873-20-5 (free base))
- WX390 Impurity 3 (CAS CATO-C4X-34313)
- n-(3-Fluoro-4-(trifluoromethyl)benzyl)piperidin-4-amine dihydrochloride (CAS 1322200-87-2)
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- Tau Peptide (307-321) trifluoroacetate salt (CAS 330456-50-3)
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