Ethyl 6-chloro-2-methyl-4-phenylquinoline-3-carboxylate CAS 22609-01-4
| CAS No. | 22609-01-4 |
| Molecular Formula | C19H16ClNO2 |
| Molecular Weight | 325.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 6-chloro-2-methyl-4-phenylquinoline-3-carboxylate (CAS 22609-01-4) is a high-purity analytical reference standard with the molecular formula C19H16ClNO2 and a molecular weight of 325.79 g/mol.
The molecular framework of Ethyl 6-chloro-2-methyl-4-phenylquinoline-3-carboxylate (C19H16ClNO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 6-chloro-2-methyl-4-phenylquinoline-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H16ClNO2 |
| Molecular Weight | 325.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- Ethyl (E)-2-(2-chloroacetyl)-3-((4-ethoxyphenyl)amino)but-2-enoate (CAS 795290-96-9)
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- Isopropyl 2-(4-chlorophenyl)quinoline-4-carboxylate (CAS 355433-91-9)
- (1R)-trans-Permethroyl Chloride (CAS 61914-47-4)
- (Tyr5.12,Lys7)-Polyphemusin II (CAS 147658-54-6)
- Methyl 2-amino-4-p-tolylthiazole-5-carboxylate (CAS 1133115-44-2)
- Methyl 6-methyl-2-oxo-4-sulfanyl-1,2-dihydropyrimidine-5-carboxylate (CAS 863669-54-9)
- Colistin B XAcetate (CAS 7239-48-7（free base）)
- 2-Cyano-3-(4-hydroxyphenyl)propanoic Acid (CAS 90924-41-7)
- 4-Chloro-N,N-diethylpyrimidin-2-amine (CAS 71406-62-7)
- 1-Acetyl-4-methylenepiperidine (CAS 308087-58-3)
- Ethyl 2-(6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetate (CAS 193979-48-5)
- Peptide Impurity 06 (CAS CATO-CPTD788806)
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