22625-57-6 5-(Chloromethyl)-1,3-oxazolidin-2-one 5-(chloromethyl)oxazolidin-2-one 5-Chloromethyl-2-oxazolidinone NSC 111158 CAS 22625-57-6
| CAS No. | 22625-57-6 |
| Molecular Formula | C4H6ClNO2 |
| Molecular Weight | 135.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
22625-57-6 5-(Chloromethyl)-1,3-oxazolidin-2-one 5-(chloromethyl)oxazolidin-2-one 5-Chloromethyl-2-oxazolidinone NSC 111158 (CAS 22625-57-6) is a high-purity analytical reference standard with the molecular formula C4H6ClNO2 and a molecular weight of 135.55 g/mol.
22625-57-6 5-(Chloromethyl)-1,3-oxazolidin-2-one 5-(chloromethyl)oxazolidin-2-one 5-Chloromethyl-2-oxazolidinone NSC 111158 (C4H6ClNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H6ClNO2 |
| Molecular Weight | 135.55 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
- (5R)-5-(chloromethyl)oxazolidin-2-one (CAS 169048-79-7)
- (5S)-5-(chloromethyl)oxazolidin-2-one (CAS 169048-83-3)
- 2-(chloromethyl)morpholine (CAS 122894-70-6)
- 2-(chloromethyl)-5-methyl-oxazole (CAS 731851-14-2)
- 3-(chloromethyl)-1-methyl-1,2,4-triazole (CAS 233278-54-1)
- (Chloromethyl)dimethylvinylsilane (CAS 16709-86-7)
- 3-(Chloromethyl)hexane (CAS 124618-04-8)
- 4-(chloromethyl)-1-methyl-imidazole (CAS 112258-59-0)
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