3'-Fluoro-[1,1'-biphenyl]-2-amine CAS 2264-92-8
| CAS No. | 2264-92-8 |
| Molecular Formula | C12H10FN |
| Molecular Weight | 187.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3'-Fluoro-[1,1'-biphenyl]-2-amine (CAS 2264-92-8) is a high-purity analytical reference standard with the molecular formula C12H10FN and a molecular weight of 187.21 g/mol.
The molecular framework of 3'-Fluoro-[1,1'-biphenyl]-2-amine (C12H10FN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10FN |
| Molecular Weight | 187.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 7-fluoro-6-methoxy-2,3-dihydro-1H-isoindol-1-one (CAS 1007455-31-3)
- 6-Fluoro-[1,1'-biphenyl]-3-amine (CAS 103977-88-4)
- 5-Fluoro-[1,1'-biphenyl]-3-amine (CAS 1214323-17-7)
- 3-(4-Fluoro-3-methylphenyl)pyridine (CAS 1214328-77-4)
- 3-(3-Fluoro-4-methylphenyl)pyridine (CAS 1214336-02-3)
- 3-(2-Fluoro-4-methylphenyl)pyridine (CAS 1214339-90-8)
- 4-(4-Fluoro-3-methylphenyl)pyridine (CAS 1214354-05-8)
- 2-Fluoro-3-methyl-5-phenylpyridine (CAS 1214362-13-6)
Recommended Standards
- 2-Fluoro-n-phenylaniline (CAS 328-20-1)
- 3-Fluoro-[1,1'-biphenyl]-2-amine (CAS 920752-43-8)
- 2-Fluoro-4-(4-methylphenyl)-pyridine (CAS 2179038-23-2)
- 3'-Fluoro-[1,1'-biphenyl]-3-amine (CAS 400751-05-5)
- Diethyl 2-(4-fluorobenzoyl)malonate (CAS 174403-79-3)
- Tirofiban HCl (CAS 142373-60-2)
- 496-74-2 U89B11P7SC Dithiol Toluene-3,4-dithiol 1,2-Benzenedithiol, 4-methyl- 4-06-00-05890 (Beilstein Handbook Reference) BRN 1635270 1,2-Dimercapto-4-methylbenzene 3,4-Dimercaptotoluene 3,4-Dimercaptotoluol EINECS 207-828-3 4-Methyl-1,2-benzenedithiol 4-Methyl-1,2-dimercaptobenzene NSC 5391 o-Toluenesulfonylamide o-Toluensulfamid [Czech] USAF B-59 o-Toluensulfamid UNII-U89B11P7SC (CAS 496-74-2)
- N-(tetrahydro-2H-pyran-4-yl)azetidin-3-amine dihydrochloride (CAS 2126159-68-8)
- 4-(Tert-butyl)-N-(2-cyanophenyl)benzenesulfonamide (CAS 943006-93-7)
- 7-Bromo-2,1,3-benzothiadiazole-4-carbonitrile (CAS 1331742-86-9)
- 2-(Difluoromethyl)-3-fluoro-6-methyl-5-nitropyridine (CAS 1804425-46-4)
- 2-(3-Methoxyphenyl)-7,8-dimethylquinoline-4-carboxylic acid (CAS 667435-75-8)
- 6-Amino-2-(o-tolylamino)pyrimidin-4(1H)-one (CAS 139296-83-6)
- Des-Phe22-Tirzepatide (CAS CATO-CPTD788951)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com