Dapagliflozin impurity 220 CAS 2266576-17-2
| CAS No. | 2266576-17-2 |
| Molecular Formula | C29H31ClO11 |
| Molecular Weight | 591.00 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dapagliflozin impurity 220.
As a process- or degradation-related impurity, Dapagliflozin impurity 220 (CAS 2266576-17-2, C29H31ClO11) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Dapagliflozin impurity 220 (C29H31ClO11) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 591.00 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dapagliflozin impurity 220 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C29H31ClO11 |
| Molecular Weight | 591.00 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
Related Dapagliflozin Standards
- Dapagliflozin Impurity 140 (CAS 912917-85-2)
- Dapagliflozin Impurity 178 (CAS CATO-C4X-1138178)
- Dapagliflozin Impurity 42 (CAS CATO-C4X-113842)
- Dapagliflozin Impurity 176 (CAS CATO-C4X-1138176)
- Dapagliflozin Impurity 145 (CAS 1971128-00-3)
- Dapagliflozin Impurity 168 (CAS CATO-C4X-1138168)
- Dapagliflozin impurity 219 (CAS 2640125-03-5)
- Dapagliflozin-3-O-Glucuronide (CAS 1351438-75-9)
Recommended Standards
- 2-((6-(4-Chlorophenyl)-3-cyano-4-(3,4-dimethoxyphenyl)pyridin-2-yl)thio)-N-(4-methoxy-2-nitrophenyl)acetamide (CAS 332127-47-6)
- E10S5M8KE4 928-24-5 Dioleoyl ethylene glycol 1,2-Ethanediyl dioleate EINECS 213-170-8 UNII-E10S5M8KE4 (CAS 928-24-5)
- Docosyl oleate (CAS 127566-70-5)
- (5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic anhydride (CAS 55726-28-8)
- Diazepam EP Impurity B (CAS 6021-21-2)
- Neratinib Impurity 2 (CAS 1144516-20-0)
- Nemonoxacin Impurity 58 (CAS CATO-C4X-312858)
- 2-Chloro-N-[4-(pyridin-2-ylsulfanyl)phenyl]pyridine-3-carboxamide (CAS 1024057-45-1)
- 2,3',4,4',5-Pentachloro[13C12]biphenyl (CAS 104130-40-7)
- N-(2-bromo-4-methylphenyl)cyclobutanecarboxamide (CAS 750623-54-2)
- N-Ethyl-3-fluorobenzylamine (CAS 90389-85-8)
- (R)-1-(4-Bromophenyl)-2,2,2-trifluoroethan-1-amine (CAS 843608-53-7)
- n-(4-Fluorobenzyl)-1-methoxybutan-2-amine (CAS 1343891-06-4)
- Neuropeptide Y (13-36) (human, rat) (CAS 122341-40-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com