2-hydroxy-n-(hydroxymethyl)acetamide 22717-93-7 AR-1E2678 CAS 22717-93-7

Purity 97%+In StockPharmaceutical Standards
CAS No.22717-93-7
Molecular FormulaC18H12O
Molecular Weight244.29 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-hydroxy-n-(hydroxymethyl)acetamide 22717-93-7 AR-1E2678 CAS 22717-93-7 chemical structure

Description

2-hydroxy-n-(hydroxymethyl)acetamide 22717-93-7 AR-1E2678 (CAS 22717-93-7) is a high-purity analytical reference standard with the molecular formula C18H12O and a molecular weight of 244.29 g/mol.

The molecular framework of 2-hydroxy-n-(hydroxymethyl)acetamide 22717-93-7 AR-1E2678 (C18H12O) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H12O
Molecular Weight244.29 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1963

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