2-[(2-Aminoethyl)amino]-4-[[3-(trifluoromethyl)phenyl]amino]-5-pyrimidinecarboxamide Hydrochloride CAS 227449-73-2
| CAS No. | 227449-73-2 |
| Molecular Formula | C14H15F3N6O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-[(2-Aminoethyl)amino]-4-[[3-(trifluoromethyl)phenyl]amino]-5-pyrimidinecarboxamide Hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2-[(2-Aminoethyl)amino]-4-[[3-(trifluoromethyl)phenyl]amino]-5-pyrimidinecarboxamide Hydrochloride (CAS 227449-73-2) is a high-purity analytical reference standard with the molecular formula C14H15F3N6OHClH2O and a molecular weight of 394.78 g/mol.
The molecular framework of 2-[(2-Aminoethyl)amino]-4-[[3-(trifluoromethyl)phenyl]amino]-5-pyrimidinecarboxamide Hydrochloride (C14H15F3N6OHClH2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H15F3N6O 2*HCl 2*H2O |
| Molecular Weight | 394.78 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2021 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 6 |
Related Aminoethyl Standards
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- N-(2-aminoethyl)-1-methyl-1H-pyrrole-2-carboxamide (CAS 1000931-92-9)
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- 4-[(2-aminoethyl)sulfamoyl]-1-methyl-1h-pyrrole-2-carboxamide (CAS 1000932-88-6)
- n-(2-Aminoethyl)-4,5-dibromo-1-methyl-1h-pyrrole-2-carboxamide (CAS 1000933-11-8)
Recommended Standards
- N-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-acetamide (CAS 948-94-7)
- Vincristine-d3 Sulfate (CAS 1217854-24-4)
- 2-(Azetidin-1-ylmethyl)-4,6-dichloropyrimidine (CAS 1873475-39-8)
- 2,2,2-Trifluoro-1-(3-fluorophenyl)ethylamine Hydrochloride (CAS 1185302-13-9)
- Abemaciclib Impurity 19 (CAS CATO-C4X-293719)
- Methyl 5-formyl-3-phenylthiophene-2-carboxylate (CAS 189756-76-1)
- Ozenoxacin Impurity 72 (CAS CATO-C4X-279672)
- 4-(1-(3-Nitrophenyl)ethyl)morpholine (CAS 1190371-32-4)
- 3-(1h-Pyrazol-1-yl)phenol (CAS 904315-14-6)
- Insulin Degludec Impurity 9 (CAS CATO-C4X-21579)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com