4-(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmethyl)-benzoic acid CAS 227598-41-6
| CAS No. | 227598-41-6 |
| Molecular Formula | C16H11NO4 |
| Molecular Weight | 281.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmethyl)-benzoic acid (CAS 227598-41-6), molecular formula C16H11NO4 and molecular weight 281.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmethyl)-benzoic acid (C16H11NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmethyl)-benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H11NO4 |
| Molecular Weight | 281.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2022 |
| Nitrogen Atoms | 1 |
Related Dioxo Standards
- 4-(4-Methyl-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzoic acid (CAS 1004085-26-0)
- 1,3-Dioxo-2-(p-tolyl)isoindoline-5-carboxylic acid (CAS 110784-06-0)
- 2-[1-(2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbonyl)piperidin-2-yl]acetic acid (CAS 1179760-33-8)
- 4-(1,3-Dioxo-2,3-dihydro-1h-isoindol-2-yl)-2-methylbenzoic acid (CAS 161291-72-1)
- Methyl 4-(2,3-dioxo-2,3-dihydro-1H-indol-5-yl) benzoate (CAS 889954-85-2)
- N-(2,4-Dioxo-1,2-dihydroquinazolin-3(4H)-yl)benzamide (CAS 75906-74-0)
- 3-(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-N-(1,3,4-thiadiazol-2-yl)propanamide (CAS 1088112-00-8)
- 7-Benzyl-1,3-dioxo-1,2,3,4,5,6,7,8-octahydro-2,7-naphthyridine-4-carbonitrile (CAS 1228692-26-9)
Recommended Standards
- 3-Ethoxycarbonylmethyl-4-oxo-10-oxa-3-aza-tricyclo[5.2.1.0*1,5*]dec-8-ene-6-carboxylic acid (CAS 436811-04-0)
- 4-(1H-Indol-1-yl)benzoic acid (CAS 71935-16-5)
- 3-Bromo-2-methoxytetrahydro-2H-pyran (CAS 5324-21-0)
- 4-(3-Azidopropoxy)-3,5-dimethoxybenzoic acid (CAS 2096986-74-0)
- Drazoxolon (CAS 5707-69-7)
- 6-Bromo-4-cyclopropoxypicolinonitrile (CAS 1243397-85-4)
- 4-Chloro-5-fluoro-2-hydroxybenzoic acid (CAS 181289-00-9)
- Norethisterone Acetate EP Impurity H (CAS 2417092-17-0)
- 4-Ethyl-5-(1-ethyl-1H-pyrazol-4-yl)-4H-1,2,4-triazole-3-thiol (CAS 1001756-07-5)
- 1-(5-Methylthiazol-4-yl)ethanamine dihydrochloride hydrate (CAS 2368828-64-0)
- (3-Chloro-4-fluoro-5-methylfuran-2-yl)(phenyl)methanol (CAS 1443340-13-3)
- 4-(3-Bromophenyl)-2-methylbut-3-yn-2-ol (CAS 76347-61-0)
- 5-Methoxy-1,3-dimethyl-1H-indole-2-carboxylic acid (CAS 59908-57-5)
- Pheromone Biosynthesis Activating Neuropeptide (Helicoverpa assulta, Heliothis zea) (CAS 122071-54-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com