Gabapentin Impurity 10 CAS 227626-60-0
| CAS No. | 227626-60-0 |
| Molecular Formula | C14H25NO4 |
| Molecular Weight | 271.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Gabapentin Impurity 10.
As a process- or degradation-related impurity, Gabapentin Impurity 10 (CAS 227626-60-0, C14H25NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Gabapentin Impurity 10 (C14H25NO4) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 271.35 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Gabapentin Impurity 10 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H25NO4 |
| Molecular Weight | 271.35 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2022 |
| Nitrogen Atoms | 1 |
Related Gabapentin Standards
- Gabapentin Impurity 36 (CAS 93727-70-9)
- Gabapentin Impurity 17 (CAS CATO-C4X-165417)
- Gabapentin Impurity 37 (CAS 79371-39-4)
- Gabapentin Impurity 16 (CAS 1281568-83-9)
- Gabapentin Impurity 22 (CAS CATO-C4X-165422)
- Gabapentin impurity 35 (CAS CATO-C4X-165435)
- Gabapentin EP Impurity D (CAS 1076198-17-8)
- Gabapentin Impurity 38 (CAS 3048030-55-0)
Recommended Standards
- Atomoxetine Impurity 51 (CAS CATO-C4X-155051)
- Apalutamide Impurity 80 (CAS CATO-C4X-274980)
- Atomoxetine Impurity 24 (CAS 435293-66-6)
- Nefopam Impurity 3 (CAS 60725-36-2)
- LCZ-696 Impurity 62 (CAS CATO-C4X-169662)
- Orforglipron impurity 78 (CAS CATO-C4X-323478)
- Linezolid Impurity 121 (CAS CATO-C4X-1073121)
- 4-Amino-1H-indazol-3-ol (CAS 89792-08-5)
- 2-(Difluoromethyl)benzo[d]oxazole-7-carboxaldehyde (CAS 1806340-41-9)
- 1-(3-(1,1,2,2-Tetrafluoroethoxy)phenyl)butan-1-ol (CAS 1443346-82-4)
- 2-Chloro-N,N-bis(cyanomethyl)benzamide (CAS 302909-49-5)
- 5-Bromo-6-fluoro-1-isopropyl-2-methylbenzimidazole (CAS 1393442-16-4)
- 2-(3H-imidazo[4,5-b]pyridin-3-yl)ethan-1-amine (CAS 885468-76-8)
- Biotinyl-S6 Phosphate Acceptor Peptide trifluoroacetate salt (CAS 1815618-12-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com