N-(2-aminoethyl)-N-(2-((carboxymethyl)amino)ethyl)glycine CAS 2276663-36-4
| CAS No. | 2276663-36-4 |
| Molecular Formula | C8H17N3O4 |
| Molecular Weight | 219.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
N-(2-aminoethyl)-N-(2-((carboxymethyl)amino)ethyl)glycine (CAS 2276663-36-4) is a certified pharmaceutical impurity reference standard with the molecular formula C8H17N3O4 and a molecular weight of 219.24 g/mol.
Structurally, N-(2-aminoethyl)-N-(2-((carboxymethyl)amino)ethyl)glycine (C8H17N3O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 219.24 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H17N3O4 |
| Molecular Weight | 219.24 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 3 |
Related N Standards
- 2,2'-((2-((2-aminoethyl)amino)ethyl)azanediyl)diacetic acid (CAS 2276662-37-2)
- 1-[4-(1-aminoethyl)phenyl]-3-cyclopropylurea (CAS 1250659-48-3)
- 1-[4-(1-aminoethyl)phenyl]-1,3-diazinan-2-one (CAS 1487077-19-9)
- (R)-2-(3-(1-Aminoethyl)-2-fluorophenyl)-2,2-difluoroethanol (CAS 2359690-81-4)
- 5-(2-Aminoethyl)-1-benzylpyrrolidin-2-one (CAS 1253654-23-7)
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- 1-(4-(2-Aminoethyl)benzyl)pyrrolidin-2-one (CAS 914200-36-5)
- N-(2-Aminoethyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (CAS 84460-89-9)
Recommended Standards
- 2,2'-((azanediylbis(ethane-2,1-diyl))bis(azanediyl))diacetic acid (CAS 98487-76-4)
- Serotonin Impurity 2 (CAS CATO-C4X-25342)
- Vazegepant impurity 33 (CAS 1061710-38-0)
- Tegoprazan Impurity 67 (CAS CATO-C4X-229767)
- Vecuronium Bromide EP Impurity F (CAS 18668-29-6)
- Nizatidine impurity 16 (CAS CATO-C4X-138016)
- Sulbactam Impurity 16 (CAS CATO-C4X-175616)
- 6-Bromo-4-methylquinolin-2-amine (CAS 942500-34-7)
- Azido-PEG2-C2-Boc (CAS 1271728-79-0)
- 1327AE 2,3-Dihydro-5H-1,4-dithiino[2,3-b]indole 352524-37-9 C10H9NS2 (CAS 352524-37-9)
- 2-bromo-6-phenylpyridin-3-amine (CAS 898568-39-3)
- N-(4-Ethoxyphenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332912-55-7)
- 5-(Aminomethyl)-1-(cyclopropylmethyl)pyridin-2(1H)-one (CAS 1400635-87-1)
- Liraglutide Sodium Salt (CAS 204656-20-2（free base）)
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