5-Oxo-5,6-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid CAS 22772-39-0
| CAS No. | 22772-39-0 |
| Molecular Formula | C8H6N2O3 |
| Molecular Weight | 178.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Oxo-5,6-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-Oxo-5,6-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid (CAS 22772-39-0) is a high-purity analytical reference standard with the molecular formula C8H6N2O3 and a molecular weight of 178.14 g/mol.
5-Oxo-5,6-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid (C8H6N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H6N2O3 |
| Molecular Weight | 178.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 2 |
Related Oxo Standards
- 2-Oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-4-carboxylic acid (CAS 1190310-95-2)
- 2-Oxo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid (CAS 1190313-18-8)
- 4-Oxo-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-3-carboxylic acid (CAS 1190314-55-6)
- 2-Oxo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-5-carboxylic acid (CAS 1190317-48-6)
- 2-Oxo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid (CAS 1190318-74-1)
- 2-Oxo-2,3-dihydro-1H-pyrrolo[2,3-c]pyridine-7-carboxylic acid (CAS 1190318-92-3)
- 2-Oxo-2,3-dihydro-1H-pyrrolo[2,3-c]pyridine-4-carboxylic acid (CAS 1190319-78-8)
- 5-Oxo-4,5-dihydro-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid (CAS 1190321-95-9)
Recommended Standards
- 5-Nitro-2-indolinone (CAS 20870-79-5)
- 5-Phenyl-1,3-dioxolane-2,4-dione (CAS 42783-36-8)
- 5-Methoxyisobenzofuran-1,3-dione (CAS 28281-76-7)
- 6-Amino-1,2-benzisoxazole-3-carboxylic acid (CAS 28691-46-5)
- (S)-1-(2-chloro-5-(trifluoromethyl)phenyl)-2-methoxyethan-1-amine (CAS 1270008-96-2)
- 2-Methyl-4-nitrobenzamide (CAS 99584-16-4)
- N,N-dimethyl-2-nitrobenzamide (CAS 2018-71-5)
- Alprostadil (Prostaglandin E1) EP Impurity A (CAS 14152-28-4)
- 1-(4-(Methylthio)phenyl)-1-(1H-pyrrol-2-yl)ethanol (CAS 944698-00-4)
- (Pentamethylcyclopentadienyl)rhodium(III) dichloride dimer (CAS 12354-85-7)
- 1-(1-(3-Bromophenyl)-1h-tetrazol-5-yl)ethan-1-amine (CAS 1266823-65-7)
- tert-butyl (2S)-2-(bromomethyl)-2,3-dihydro-1H-indole-1-carboxylate (CAS 2348332-97-6)
- 2-(Furan-2-yl)-1-tosylpiperidine (CAS 1355181-83-7)
- 59880-97-6 Chemotactic peptide F-Met-Leu-Phe L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)- N-Formyl-L-methionyl-L-leucyl-L-phenylalanine N-Formyl-Met-Leu-Phe N-Formylmethionine leucyl-phenylalanine fMLF fMLP (misnomer but widely used) (CAS 59880-97-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com