2-((1s,3s)-3-(Trifluoromethoxy)cyclobutoxy)acetic acid CAS 2278281-70-0
| CAS No. | 2278281-70-0 |
| Molecular Formula | C7H9F3O4 |
| Molecular Weight | 214.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-((1s,3s)-3-(Trifluoromethoxy)cyclobutoxy)acetic acid (CAS 2278281-70-0), molecular formula C7H9F3O4 and molecular weight 214.14 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 2-((1s,3s)-3-(Trifluoromethoxy)cyclobutoxy)acetic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 214.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2-((1s,3s)-3-(Trifluoromethoxy)cyclobutoxy)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H9F3O4 |
| Molecular Weight | 214.14 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
Recommended Standards
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