5-Amino-2-methoxy-N,N-dimethylbenzamide CAS 22802-73-9
| CAS No. | 22802-73-9 |
| Molecular Formula | C10H14N2O2 |
| Molecular Weight | 194.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Amino-2-methoxy-N,N-dimethylbenzamide (CAS 22802-73-9) is a high-purity analytical reference standard with the molecular formula C10H14N2O2 and a molecular weight of 194.23 g/mol.
The molecular framework of 5-Amino-2-methoxy-N,N-dimethylbenzamide (C10H14N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Amino-2-methoxy-N,N-dimethylbenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14N2O2 |
| Molecular Weight | 194.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 2-(2-Amino-5-methylphenoxy)-n-methylacetamide (CAS 1016769-07-5)
- 2-Amino-N-(4-ethoxyphenyl)acetamide (CAS 103-97-9)
- Ethyl 2-amino-3-(pyridin-4-yl)propanoate (CAS 103392-91-2)
- ethyl 2-amino-3-(pyridin-2-yl)propanoate (CAS 103394-76-9)
- n-(4-(2-Amino-1-hydroxyethyl)phenyl)acetamide (CAS 1038241-55-2)
- Methyl 3-amino-2-(pyridin-4-ylmethyl)propanoate (CAS 1038703-97-7)
- Methyl 3-amino-2-(pyridin-2-ylmethyl)propanoate (CAS 1038704-50-5)
- 3-Amino-5-methoxy-N,N-dimethylbenzamide (CAS 1050513-84-2)
Recommended Standards
- 5-Amino-1-cyclopentyl-1H-pyrazole-4-carboxamide (CAS 666235-33-2)
- 5-Amino-3-methyl-isothiazole-4-sulfonic acid (CAS 4590-59-4)
- 5-Amino-1-cyclopentyl-1H-imidazole-4-carboxamide (CAS 37642-55-0)
- 5-Ethyl-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid (CAS 856437-81-5)
- (4-(Furan-2-carbonyl)piperazin-1-yl)(2-methyl-3-nitrophenyl)methanone (CAS 825598-07-0)
- N-(2,5-difluorophenyl)-4-(pyridin-2-yl)piperazine-1-carboxamide (CAS 1024572-82-4)
- 4-Isopropyl-2-methylphenethyl Alcohol (CAS 67634-10-0)
- 3-Bromo-1-methyl-1H-indazol-5-ylamine, 97% (CAS 1092351-49-9)
- 4-Chloro-7-(trifluoromethyl)-5,6,7,8-tetrahydroquinazoline (CAS 1256955-47-1)
- 1-Phenyl-1h-pyrrole-2-carbonitrile (CAS 35524-46-0)
- N-Cyclohexyl-3-bromobenzenesulfonamide (CAS 871269-10-2)
- 6-(2-(4-Chlorophenyl)thiazol-5-yl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 1209767-73-6)
- 8-(((2r,5r)-5-Amino-1,3-dioxan-2-yl)methyl)-6-(2-chloro-4-(6-methylpyridin-2-yl)phenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (CAS 1648863-90-4)
- Semaglutide impurity 255 (CAS CATO-C4X-2226255)
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