2-(3,5-Bis(trifluoromethyl)phenyl)-2-hydroxyacetic acid CAS 228107-82-2
| CAS No. | 228107-82-2 |
| Molecular Formula | C10H6F6O3 |
| Molecular Weight | 288.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(3,5-Bis(trifluoromethyl)phenyl)-2-hydroxyacetic acid (C10H6F6O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 2-(3,5-Bis(trifluoromethyl)phenyl)-2-hydroxyacetic acid (CAS 228107-82-2), a certified reference material (molecular formula C10H6F6O3, MW 288.14 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(3,5-Bis(trifluoromethyl)phenyl)-2-hydroxyacetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6F6O3 |
| Molecular Weight | 288.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2022 |
| Halogen Content | F-containing |
Related Bis Standards
- 3,5-Bis(trifluoromethyl)-2-methoxybenzoic acid (CAS 197015-74-0)
- 2-[3,5-bis(trifluoromethyl)phenoxy]acetic acid (CAS 87964-30-5)
- 1,3,5-Tris(trifluoromethyl)cyclohexane (CAS 1177349-24-4)
- 188781-15-9 Ethyl-2-trifluoromethyl-4-trifluoromethyl-5-pyrimidine carboxylate ethyl 2,4-bis(trifluoromethyl)pyrimidine-5-carboxylate (CAS 188781-15-9)
- Bis(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)methane (CAS 5228-95-5)
- 1-(3,5-Bis(trifluoromethyl)phenyl)thiourea (CAS 175277-17-5)
- 3-(Trifluoromethyl)-4-(4,4,6-trimethyl-1,3,2-dioxaborinan-2-yl)phenol (CAS 2096994-58-8)
- 4-(Trifluoromethyl)-2-(4,4,6-trimethyl-1,3,2-dioxaborinan-2-yl)phenol (CAS 2096998-36-4)
Recommended Standards
- 2-(2-Bromo-4-methylphenoxy)-N-(2-hydroxyethyl)acetamide (CAS 690986-73-3)
- 2-(3-Bromophenoxy)-N-(2-methoxyethyl)acetamide (CAS 449169-55-5)
- 2-(1H-Benzo[d]imidazol-2-yl)-4-bromoaniline (CAS 77123-67-2)
- 2-(3-Bromophenyl)-7-methylimidazo[1,2-a]pyrimidine (CAS 864685-42-7)
- 6-Chloro-N-(2-(2-methyl-1H-imidazol-1-yl)ethyl)benzo[d]thiazol-2-amine (CAS 1219914-58-5)
- 2-(4-Bromophenyl)-4,5-dimethyl-1h-imidazole (CAS 732192-01-7)
- 2-(5-Amino-3-(pyridin-4-yl)-1h-pyrazol-1-yl)ethan-1-ol (CAS 14550-40-4)
- 3-Amino-4-(propylamino)benzene-1-sulfonamide (CAS 851175-89-8)
- Rocuronium Bromide Impurity 23 (CAS CATO-C4X-124223)
- 3-Amino-1-(2,4-dimethylphenyl)propan-1-ol (CAS 1215954-90-7)
- 4-Methyl-2-(3-oxobenzo[d]isothiazol-2(3h)-yl)pentanoic acid (CAS 1539497-03-4)
- 2-((1-Ethyl-5-phenyl-1H-imidazol-2-yl)thio)-N-phenylacetamide (CAS 1207025-24-8)
- Ethyl 4,6-dibromo-1H-indole-2-carboxylate (CAS 704909-87-5)
- Galanin Message Associated Peptide (1-41) amide trifluoroacetate salt (CAS 132699-74-2)
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