2-(4-Fluorophenyl)-4,5-diphenyl-1H-imidazole CAS 2284-96-0
| CAS No. | 2284-96-0 |
| Molecular Formula | C21H15FN2 |
| Molecular Weight | 314.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(4-Fluorophenyl)-4,5-diphenyl-1H-imidazole (C21H15FN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(4-Fluorophenyl)-4,5-diphenyl-1H-imidazole (CAS 2284-96-0) is a high-purity analytical reference standard with the molecular formula C21H15FN2 and a molecular weight of 314.36 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-Fluorophenyl)-4,5-diphenyl-1H-imidazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H15FN2 |
| Molecular Weight | 314.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- 2-((3-(4-Fluorophenyl)imidazo[1,2-b]pyridazin-6-yl)amino)-3-methylbutan-1-ol (CAS 1012343-82-6)
- 2-(((2-(4-Fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl)methyl)thio)acetic acid (CAS 1387445-04-6)
- (5R)-5-(4-{[(2-fluorophenyl)methyl]oxy}phenyl)-L-prolinamide (CAS 934240-30-9)
- 1-(4-(2-Fluorophenyl)piperazin-1-yl)-2-phenoxyethan-1-one (CAS 438474-62-5)
- (1-(4-Fluorophenyl)-3-(4-(methylthio)phenyl)-1H-pyrazol-4-yl)methanol (CAS 618444-46-5)
- 3-(2-Fluorophenyl)-2-methyl-2,3,5,6-tetrahydro-4H-2,6-methanobenzo[g][1,3,5]oxadiazocine-4-thione (CAS 946294-64-0)
- 3-(4-Fluorophenyl)-2-methyl-2,3,5,6-tetrahydro-4H-2,6-methanobenzo[g][1,3,5]oxadiazocine-4-thione (CAS 702655-62-7)
- 5-(((4-Fluorophenyl)amino)methyl)-4-(m-tolyl)-4H-1,2,4-triazole-3-thiol (CAS 917750-15-3)
Recommended Standards
- 2-(4-(Dimethylamino)benzylidene)-6-methyl-2H-thiazolo[3,2-b][1,2,4]triazine-3,7-dione (CAS 463364-55-8)
- 2-(5-(3,4-Dimethylphenyl)-4-oxothieno[2,3-d]pyrimidin-3(4H)-yl)acetic acid (CAS 446830-86-0)
- 2-(1-(Benzo[d][1,2,3]thiadiazol-5-yl)-2,5-dimethyl-1H-pyrrol-3-yl)-N-methyl-2-oxoacetamide (CAS 866156-77-6)
- 2-(6-Methyl-4-oxo-5-phenylthieno[2,3-d]pyrimidin-3(4H)-yl)propanoic acid (CAS 685549-79-5)
- 4-Bromo-3-chlorobenzene-1-sulfonyl chloride (CAS 874801-46-4)
- Dibutylamine acetate concentrate (CAS 19070-91-8)
- BC-11-38 (CAS 686770-80-9)
- (4-Nitro-1H-indazol-3-yl)methanol (CAS 1934930-69-4)
- 2-((4-Ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-fluorophenyl)acetamide (CAS 557065-87-9)
- Sertraline Impurity 70 (CAS CATO-C4X-134470)
- (4-Bromophenyl)(4-fluoro-3-methylphenyl)methanone (CAS 844879-20-5)
- 3-Amino-5-(furan-2-yl)benzoic acid (CAS 1262010-42-3)
- 2-(3-Fluorophenyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine (CAS 1485111-61-2)
- Neuropeptide Y (13-36) (human, rat) (CAS 122341-40-6)
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