Ethyl 8-fluoro-4-hydroxy-6-iodoquinoline-3-carboxylate CAS 228728-08-3

Description

The occurrence of Ethyl 8-fluoro-4-hydroxy-6-iodoquinoline-3-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Ethyl 8-fluoro-4-hydroxy-6-iodoquinoline-3-carboxylate (CAS 228728-08-3) is a high-purity analytical reference standard with the molecular formula C12H9FINO3 and a molecular weight of 361.11 g/mol.

The molecular framework of Ethyl 8-fluoro-4-hydroxy-6-iodoquinoline-3-carboxylate (C12H9FINO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures Ethyl 8-fluoro-4-hydroxy-6-iodoquinoline-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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