4-Hydroxy-6-iodoquinoline-3-carboxylic acidethylester CAS 228728-23-2

Purity 97%+In StockPharmaceutical Standards
CAS No.228728-23-2
Molecular FormulaC12H10INO3
Molecular Weight343.12 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Hydroxy-6-iodoquinoline-3-carboxylic acidethylester CAS 228728-23-2 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

4-Hydroxy-6-iodoquinoline-3-carboxylic acidethylester (CAS 228728-23-2), molecular formula C12H10INO3 and molecular weight 343.12 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution, 4-Hydroxy-6-iodoquinoline-3-carboxylic acidethylester is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 343.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

As a certified reference material (CRM), 4-Hydroxy-6-iodoquinoline-3-carboxylic acidethylester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H10INO3
Molecular Weight343.12 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2022
Halogen ContentI-containing
Nitrogen Atoms1

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