Urapidil Impurity 80 CAS 2287493-08-5
| CAS No. | 2287493-08-5 |
| Molecular Formula | C8H12ClN3O2 |
| Molecular Weight | 217.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Urapidil Impurity 80 (C8H12ClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 217.65 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Urapidil Impurity 80 (CAS 2287493-08-5), a pharmacopoeial impurity reference standard (molecular formula C8H12ClN3O2, MW 217.65 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H12ClN3O2 |
| Molecular Weight | 217.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Urapidil Standards
- Urapidil Impurity 29 (CAS 34654-88-1)
- Urapidil Impurity 80 (CAS CATO-C4X-192480)
- Urapidil Impurity 66 (CAS 2219339-64-5)
- Urapidil Impurity 1 (CAS 34654-80-3)
- Urapidil Impurity 19 (CAS 2287518-97-0)
- Urapidil Impurity 55 (CAS CATO-C4X-192455)
- Urapidil Impurity 113 (CAS CATO-C4X-1924113)
- Urapidil Impurity 69 (CAS 117525-95-8)
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- 5-[(4-methyl-1H-pyrazol-1-yl)methyl]-1,2-oxazole-3-carboxylic acid (CAS 1170258-35-1)
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- 2-(4-Chlorophenyl)-2-oxoethyl 4-hydroxybenzoate (CAS 386730-85-4)
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- (R)-2-(Pyrrolidin-2-yl)-1H-benzo[d]imidazole (CAS 175530-90-2)
- [His]1-Acetylated Semaglutide (CAS CATO-C4X-2226219)
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