2-chloro-N-[(2-nitrophenyl)methyl]acetamide CAS 22896-07-7
| CAS No. | 22896-07-7 |
| Molecular Formula | C9H9ClN2O3 |
| Molecular Weight | 228.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-chloro-N-[(2-nitrophenyl)methyl]acetamide.
2-chloro-N-[(2-nitrophenyl)methyl]acetamide (CAS 22896-07-7), molecular formula C9H9ClN2O3 and molecular weight 228.63 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-chloro-N-[(2-nitrophenyl)methyl]acetamide (C9H9ClN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-chloro-N-[(2-nitrophenyl)methyl]acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H9ClN2O3 |
| Molecular Weight | 228.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 2-Chloro-N,N-dimethyl-5-nitrobenzamide (CAS 60587-79-3)
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- 3-Cyclopentyl-1-({1-[4-methyl-2-(pyridin-3-yl)-1,3-thiazol-5-yl]ethylidene}amino)urea (CAS 1356819-44-7)
- 2-(2-Aminopropyl)-3a,4,7,7a-tetrahydro-1h-isoindole-1,3(2h)-dione (CAS 1342458-56-3)
- 7-Methoxy-2,5-dimethylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 739364-97-7)
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- Neuroendocrine Regulatory Peptide-1 (human) (H-6622.1000) (CAS 954420-50-9)
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