2290-65-5 Trimethylsilylisothiocyanate Silane, isothiocyanatotrimethyl- Trimethylsilyl isothiocyanate EINECS 218-929-7 Isothiocyanatotrimethylsilane CAS 2290-65-5
| CAS No. | 2290-65-5 |
| Molecular Formula | C4H9NSSi |
| Molecular Weight | 131.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2290-65-5 Trimethylsilylisothiocyanate Silane, isothiocyanatotrimethyl- Trimethylsilyl isothiocyanate EINECS 218-929-7 Isothiocyanatotrimethylsilane.
2290-65-5 Trimethylsilylisothiocyanate Silane, isothiocyanatotrimethyl- Trimethylsilyl isothiocyanate EINECS 218-929-7 Isothiocyanatotrimethylsilane (CAS 2290-65-5), molecular formula C4H9NSSi and molecular weight 131.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2290-65-5 Trimethylsilylisothiocyanate Silane, isothiocyanatotrimethyl- Trimethylsilyl isothiocyanate EINECS 218-929-7 Isothiocyanatotrimethylsilane (C4H9NSSi) is characterized by sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2290-65-5 Trimethylsilylisothiocyanate Silane, isothiocyanatotrimethyl- Trimethylsilyl isothiocyanate EINECS 218-929-7 Isothiocyanatotrimethylsilane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H9NSSi |
| Molecular Weight | 131.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Recommended Standards
- Bis(dimethylamino)methylsilane (CAS 22705-33-5)
- (3-Aminopropyl)trimethylsilane (CAS 18187-14-9)
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