(5-Chloro-2-nitrophenyl)acetic Acid CAS 22908-28-7
| CAS No. | 22908-28-7 |
| Molecular Formula | C8H6ClNO4 |
| Molecular Weight | 215.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (5-Chloro-2-nitrophenyl)acetic Acid.
(5-Chloro-2-nitrophenyl)acetic Acid (CAS 22908-28-7), molecular formula C8H6ClNO4 and molecular weight 215.59 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (5-Chloro-2-nitrophenyl)acetic Acid (C8H6ClNO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (5-Chloro-2-nitrophenyl)acetic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClNO4 |
| Molecular Weight | 215.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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- 2-Chloro-N-(3-nitropyridin-2-yl)acetamide (CAS 1065483-83-1)
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- Methyl 2-chloro-4-nitrobenzoate (CAS 13324-11-3)
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Recommended Standards
- (2-Chloro-6-nitrophenyl)acetic acid (CAS 31912-08-0)
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- 2-(2-Chloro-4-nitrophenyl)acetic Acid (CAS 73088-11-6)
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Why CATO?
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