6-Bromo-7-methoxy-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one CAS 2292109-49-8
| CAS No. | 2292109-49-8 |
| Molecular Formula | C7H6BrN3O2 |
| Molecular Weight | 244.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-Bromo-7-methoxy-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one (C7H6BrN3O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
6-Bromo-7-methoxy-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one (CAS 2292109-49-8), molecular formula C7H6BrN3O2 and molecular weight 244.05 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6BrN3O2 |
| Molecular Weight | 244.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
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Recommended Standards
- 4-Bromopyridine-2,6-dicarboxamide (CAS 668992-72-1)
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- 1-(Difluoromethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazole (CAS 2411630-87-8)
- 2-Bromo-5-(bromomethyl)-4-methoxypyridine (CAS 1807023-86-4)
- 2-(6-Bromopyridin-3-yl)-5-trifluoromethyl-1H-benzoimidazole (CAS 1370534-54-5)
- 6-(Dimethylamino)quinolin-2(1H)-one (CAS 238756-51-9)
- 1-(3-Bromo-2-chloro-6-fluorophenyl)ethan-1-one (CAS 1704367-13-4)
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- (S)-N-Boc-4-(2-iodoethyl)-2,2-dimethyloxazolidine (CAS 443123-89-5)
- (4-Isopropoxyphenyl)(oxazol-2-yl)methanone (CAS 898760-01-5)
- 110207-62-0 Acetyl-Cholecystokinin Octapeptide (2-8) (sulfated) MFCD00133565 (CAS 110207-62-0)
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