1-Hydroxy-2,2,6,6-tetramethylpiperidin-4-one hydrochloride CAS 22963-71-9
| CAS No. | 22963-71-9 |
| Molecular Formula | C9H17NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-Hydroxy-2,2,6,6-tetramethylpiperidin-4-one hydrochloride (CAS 22963-71-9), molecular formula C9H17NO2HCl and molecular weight 207.70 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Hydroxy-2,2,6,6-tetramethylpiperidin-4-one hydrochloride (C9H17NO2HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 1-Hydroxy-2,2,6,6-tetramethylpiperidin-4-one hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H17NO2 HCl |
| Molecular Weight | 207.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- N-(4-Hydroxy-3-oxo-2,3-dihydro-1H-inden-5-yl)acetamide (CAS 1000333-88-9)
- 1-Benzyl-4-hydroxy-6-carbomoyl-5-azaindole (CAS 1000342-24-4)
- 3-Hydroxy-4-cyano (1H)Indazole (CAS 1000342-91-5)
- 6-Hydroxy-1,2-dihydro-3H-indazol-3-one (CAS 1000343-86-1)
- 3-Hydroxy-5-ethylisoxazole (CAS 10004-45-2)
- 2-(6-Hydroxy-2,3-dihydrobenzofuran-3-yl)acetic acid (CAS 1000414-37-8)
- (S)-(6-Hydroxy-2,3-dihydrobenzofuran-3-yl)acetic Acid Methyl Ester (CAS 1000414-38-9)
- 2-Hydroxy-2-phenyl-1-(1H-pyrrol-2-yl)ethanone (CAS 100063-06-7)
Recommended Standards
- 5-(Cyclopropanecarbonyl)-2,2-dimethylcyclopentan-1-one (CAS 1521695-19-1)
- L-(+)-Ergothioneine-d9 (CAS CATO-CCAD303761)
- (5Z,8Z,11Z,14Z)-N-(cyclopropyl-2,2,3,3-d4)icosa-5,8,11,14-tetraenamide (CAS 1346606-69-6)
- 1-[2-(2,5-dimethyl-1H-pyrrol-1-yl)ethyl]piperazine,2HCl (CAS 5059-36-9)
- (E)-4-(4-Nitrostyryl)-N-octadecylaniline (CAS 110138-83-5)
- tert-Butyl 4-(3-((2-ethoxy-2-oxoethyl)carbamoyl)-4-nitrophenyl)piperazine-1-carboxylate (CAS 959246-47-0)
- 3-Phenyl-1-(phenylsulfonyl)-1H-indole (CAS 153827-73-7)
- Methyl 4-hydroxy-2-(hydroxymethyl)benzoate (CAS 864922-20-3)
- 2-Thiomethyl-4-thiomorpholinomethyl benzophenone (CAS 898782-55-3)
- Liraglutide Impurity 21 TFA Salt (CAS CATO-C4X-199221)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com