Ethyl 2-(3,3-difluoro-1-hydroxycyclobutyl)acetate CAS 2298347-24-5
| CAS No. | 2298347-24-5 |
| Molecular Formula | C8H12F2O3 |
| Molecular Weight | 194.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 2-(3,3-difluoro-1-hydroxycyclobutyl)acetate.
Ethyl 2-(3,3-difluoro-1-hydroxycyclobutyl)acetate (CAS 2298347-24-5), molecular formula C8H12F2O3 and molecular weight 194.18 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Ethyl 2-(3,3-difluoro-1-hydroxycyclobutyl)acetate (C8H12F2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 194.18 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H12F2O3 |
| Molecular Weight | 194.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
Related Ethyl Standards
- 4,4-Difluoro-1-methoxycyclohexane-1-carboxylic acid (CAS 1447942-28-0)
- 2,2-Difluoro-2-(1-hydroxy-2-methylcyclopentyl)acetic acid (CAS 1481020-61-4)
- Methyl 4,4-difluoro-1-hydroxycyclohexane-1-carboxylate (CAS 1803553-38-9)
- 2,2-Difluoro-2-(1-hydroxy-3-methylcyclopentyl)acetic acid (CAS 681240-29-9)
- 2,2-Difluoro-2-(1-hydroxycyclohexyl)acetic acid (CAS 206346-77-2)
- 4,5-Difluoro-2-(1H-pyrrol-1-yl)aniline (CAS 896429-38-2)
- 5,8-Difluoro-2-methylquinolin-4-amine (CAS 288151-30-4)
- 7,8-Difluoro-2-methylquinolin-4-amine (CAS 288151-48-4)
Recommended Standards
- Ethyl 2-(2-hydroxyphenyl)-2-oxoacetate (CAS 40785-55-5)
- Ethyl 2-(4-hydroxyphenyl)-2-oxoacetate (CAS 70080-54-5)
- Di(prop-2-yn-1-yl) succinate (CAS 4580-40-9)
- ethyl 2,2-difluoro-2-(1H-pyrazol-4-yl)acetate (CAS 1987228-20-5)
- 1-(1H-Pyrrolo[3,2-b]pyridin-5-yl)ethanone (CAS 1445856-03-0)
- 2-(Methylamino)-1-(1-piperidinyl)-1-ethanonehydrochloride (CAS 98998-32-4)
- Methyl 2-formyl-3,5-dihydroxybenzoate (CAS 16849-78-8)
- 2-(3,5-Dimethyl-1H-1,2,4-triazol-1-yl)ethanamine hydrochloride (CAS 1993128-72-5)
- 6-Hydroxypyridine-2-boronic Acid Pinacol Ester (CAS 1310405-04-9)
- 4-Chloro-2-methylpyrimidine-5-carbaldehyde (CAS 933686-05-6)
- Benzo[d][1,3]dioxol-5-ylmethyl 4-(3-bromo-4-hydroxy-5-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 5602-26-6)
- Boc-Dab(Fmoc)-OH (CAS 117106-21-5)
- 2-Chloro-4-methoxy-3-methylquinoline (CAS 2299199-12-3)
- semaglutide (CAS 782487-28-9)
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