1-ethyl-2,5-difluoro-1H-1,3-benzodiazole CAS 2300872-77-7
| CAS No. | 2300872-77-7 |
| Molecular Formula | C9H8F2N2 |
| Molecular Weight | 182.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-ethyl-2,5-difluoro-1H-1,3-benzodiazole.
1-ethyl-2,5-difluoro-1H-1,3-benzodiazole (CAS 2300872-77-7), molecular formula C9H8F2N2 and molecular weight 182.17 g/mol, is a CATO reference standard with documented purity and traceability.
1-ethyl-2,5-difluoro-1H-1,3-benzodiazole (C9H8F2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-ethyl-2,5-difluoro-1H-1,3-benzodiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8F2N2 |
| Molecular Weight | 182.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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- 4,6-Difluoro-1,3-dimethyl-1H-indazole (CAS 1329167-03-4)
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Recommended Standards
- 1-ethyl-2,4-difluoro-1H-1,3-benzodiazole (CAS 2298542-40-0)
- 1-ethyl-2,6-difluoro-1H-1,3-benzodiazole (CAS 2297543-94-1)
- 1-ethoxy-4-ethynyl-2,3-difluorobenzene (CAS 928208-56-4)
- 2-(2-(Hydroxymethyl)phenoxy)acetic acid (CAS 97388-49-3)
- N-(Furan-2-ylmethylene)-3-methylaniline (CAS 134127-17-6)
- 4-Amino-3-(difluoromethyl)-5-fluoropicolinoyl chloride (CAS 1805078-82-3)
- 3-Fluoroquinolin-5-ol (CAS 1261729-67-2)
- Methyl (2,6-dimethylphenyl)glycinate (CAS 55883-02-8)
- 4’-Heptyl-4-hydroxybiphenyl (CAS 82832-74-4)
- Letermovir Impurity 135 (CAS CATO-C4X-2915135)
- 4-bromooxazole;hydrochloride (CAS 1955531-81-3)
- 3-Bromo-4-chloro-5-fluorophenacyl bromide (CAS 1807036-40-3)
- 4,5-Dibromopentanoic acid (CAS 78181-02-9)
- Semaglutide impurity 195 (CAS CATO-C4X-2226195)
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