3,6-difluoropyridin-2-amine hydrochloride CAS 2305079-69-8
| CAS No. | 2305079-69-8 |
| Molecular Formula | C5H4F2N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 166.56 g/mol gives 3,6-difluoropyridin-2-amine hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3,6-difluoropyridin-2-amine hydrochloride (CAS 2305079-69-8) is a high-purity analytical reference standard with the molecular formula C5H4F2N2HCl and a molecular weight of 166.56 g/mol.
The molecular framework of 3,6-difluoropyridin-2-amine hydrochloride (C5H4F2N2HCl) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H4F2N2 HCl |
| Molecular Weight | 166.56 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related difluoropyridin Standards
- 2-(3,5-Difluoropyridin-2-yl)ethan-1-ol (CAS 1000506-82-0)
- 2-(3,5-difluoropyridin-2-yl)ethan-1-amine (CAS 1000538-73-7)
- 2-(3,5-Difluoropyridin-2-yl)acetonitrile (CAS 1000557-40-3)
- (2,6-Difluoropyridin-4-yl)methanol (CAS 1006299-98-4)
- (3,5-difluoropyridin-2-yl)methanol (CAS 1065267-14-2)
- 1-(3,5-Difluoropyridin-2-yl)ethan-1-aminehydrochloride (CAS 1065267-25-5)
- (2,6-Difluoropyridin-3-yl)boronic acid hydrate (CAS 1072952-27-2)
- 1-(3,5-Difluoropyridin-2-yl)ethanone (CAS 1075756-90-9)
Recommended Standards
- 2-(Dibenzo[b,d]furan-2-yl)benzo[d]thiazole (CAS 51412-57-8)
- methyl 1-(benzyloxycarbonylamino)cyclopropanecarboxylate (CAS 84677-05-4)
- 1-Benzyl-4-((methylamino)methyl)piperidin-4-ol (CAS 77211-74-6)
- Methyl 4-(dimethylamino)-2-hydroxy-5-iodobenzoate (CAS 1143579-89-8)
- (E)-3-((4-iodophenyl)amino)-1-(2-phenylthiazol-5-yl)prop-2-en-1-one (CAS 338414-57-6)
- 5-Bromo-2-(difluoro(3,4,5-trifluorophenoxy)methyl)-1,3-difluorobenzene (CAS 511540-64-0)
- (S)-2,2,2-Trifluoro-1-(2-fluorophenyl)ethanamine (CAS 1213370-95-6)
- Diethyl 6-chloro-8-methylquinoline-2,3-dicarboxylate (CAS 948289-50-7)
- Loxoprofen impurity 94 (CAS CATO-C4X-148894)
- D-Tyr10-Tirzepatide (CAS CATO-CPTD788922)
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