Azacitidine Impurity 74 CAS 2306050-23-5
| CAS No. | 2306050-23-5 |
| Molecular Formula | C13H20N4O9 |
| Molecular Weight | 376.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Azacitidine Impurity 74 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Azacitidine Impurity 74 (CAS 2306050-23-5) is a certified pharmaceutical impurity reference standard with the molecular formula C13H20N4O9 and a molecular weight of 376.32 g/mol.
The molecular framework of Azacitidine Impurity 74 (C13H20N4O9) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C13H20N4O9 |
| Molecular Weight | 376.32 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 4 |
Related Azacitidine Standards
- Azacitidine Impurity 25 (CAS CATO-C4X-138825)
- Azacitidine Impurity 75 (CAS CATO-C4X-138875)
- Azacitidine Impurity 87 (CAS CATO-C4X-138887)
- Azacitidine Impurity 19 (CAS CATO-C4X-138819)
- Azacitidine Impurity 36 (CAS 10302-78-0)
- Azacitidine Impurity 13 (CAS CATO-C4X-138813)
- Azacitidine Impurity 76 (CAS CATO-C4X-138876)
- Azacitidine Impurity 84 (CAS CATO-C4X-138884)
Recommended Standards
- Methyl 4-(6-nitro-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)benzoate (CAS 302954-91-2)
- Helioxanthin 8-1 (CAS 840529-13-7)
- Uridine Impurity 4 (CAS 198267-18-4)
- 4,8-Disulfonaphthalene-2,6-dicarboxylic acid (CAS 742641-46-9)
- Empagliflozin impurity 234 (CAS 1417573-74-0)
- Lubiprostone Impurity 40 (CAS CATO-C4X-113640)
- Amlodipine Impurity 147 (CAS CATO-C4X-1095147)
- (5-Chloro-2-hydroxy-3-methylphenyl)(cyclopropyl)methanone (CAS 1249780-05-9)
- Bimatoprost Impurity 19 (CAS 41639-71-8)
- 2-(Pyrrolidin-3-yl)-1,2,3,4-tetrahydroisoquinoline (CAS 1220174-41-3)
- BMS 795311 (CAS 939390-99-5)
- tert-butyl (3R)-3-hydroxyazepane-1-carboxylate (CAS 1493733-00-8)
- n-Methyl-n-[(pyrrolidin-2-yl)methyl]aniline (CAS 1021244-37-0)
- MCH-Gene-Overprinted-Polypeptide-14 (rat) (H-4746.0500) (CAS 182917-44-8)
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