7-(2,2-Difluoroethoxy)-5-fluoro-1,2,3,4-tetrahydroisoquinoline CAS 2306262-12-2
| CAS No. | 2306262-12-2 |
| Molecular Formula | C11H12F3NO |
| Molecular Weight | 231.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
7-(2,2-Difluoroethoxy)-5-fluoro-1,2,3,4-tetrahydroisoquinoline (CAS 2306262-12-2) is a high-purity analytical reference standard with the molecular formula C11H12F3NO and a molecular weight of 231.21 g/mol.
The molecular framework of 7-(2,2-Difluoroethoxy)-5-fluoro-1,2,3,4-tetrahydroisoquinoline (C11H12F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 7-(2,2-Difluoroethoxy)-5-fluoro-1,2,3,4-tetrahydroisoquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12F3NO |
| Molecular Weight | 231.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoroethoxy Standards
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- 1-(4-(2,2-Difluoroethoxy)-3-methoxyphenyl)ethan-1-amine (CAS 1178711-09-5)
- 4-(2,2-Difluoroethoxy)-3-nitrobenzaldehyde (CAS 1178251-98-3)
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- 2-(2,2-difluoroethoxy)-4-methoxybenzoic acid (CAS 937602-72-7)
- Methyl 3-(2,2-difluoroethoxy)-5-hydroxybenzoate (CAS 2597914-28-6)
- 6-(2,2-Difluoroethoxy)-1,3-benzothiazol-2-amine (CAS 1855888-91-3)
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Recommended Standards
- 6-methyl-2-(3-nitrophenyl)pyrimidine 1-oxide (CAS 210036-45-6)
- 7-(Hydroxyimino)-8,9-dihydro-2,9a-diazabenzo[cd]azulene-1,6(2H,7H)-dione (CAS 92260-82-7)
- 6-Amino-1,3-dioxolo[4,5-g]quinoline-7-carboxamide (CAS 55149-47-8)
- 7-Amino-1-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalen-1-ol (CAS 919278-33-4)
- 4-(Cyclopent-2-en-1-yl)phenol (CAS 6627-84-5)
- 6-Chloro-3-(difluoromethyl)-5-methylpicolinonitrile (CAS 1805259-55-5)
- 4-(4-Phenyl-3-(trifluoromethyl)isoxazol-5-yl)benzene-1,3-diol (CAS 904508-85-6)
- 2-(2-Isopropyl-4-methoxyphenyl)-4-methylpyrrolidine (CAS 603069-08-5)
- Methyl 4-((tert-butoxycarbonyl)amino)-2-methoxybenzoate (CAS 883555-08-6)
- 5-[2-(Trifluoromethyl)phenyl]-1H-pyrrole-3-carbaldehyde (CAS 881674-60-8)
- 3-(6-(Pyrrolidin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanoic acid (CAS 913527-48-7)
- (2S,3S)-1-benzhydryl-2-methylazetidin-3-amine (CAS 164906-71-2)
- 4-(3-(Cyclopentylamino)imidazo[1,2-a]pyrazin-2-yl)phenol (CAS 876710-97-3)
- Semaglutide impurity 36 (CAS CATO-C4X-222636)
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