Ethyl 7-bromo-3-fluoroimidazo[1,2-a]pyridine-2-carboxylate CAS 2306263-38-5
| CAS No. | 2306263-38-5 |
| Molecular Formula | C10H8BrFN2O2 |
| Molecular Weight | 287.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 7-bromo-3-fluoroimidazo[1,2-a]pyridine-2-carboxylate.
Ethyl 7-bromo-3-fluoroimidazo[1,2-a]pyridine-2-carboxylate (CAS 2306263-38-5), molecular formula C10H8BrFN2O2 and molecular weight 287.09 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 7-bromo-3-fluoroimidazo[1,2-a]pyridine-2-carboxylate (C10H8BrFN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8BrFN2O2 |
| Molecular Weight | 287.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
- 5-(2-Bromo-4-fluorophenyl)-5-methylimidazolidine-2,4-dione (CAS 1251925-16-2)
- Ethyl 6-bromo-8-fluoroimidazo[1,2-a]pyridine-2-carboxylate (CAS 1260763-32-3)
- 5-(5-Bromo-2-fluorophenyl)-5-methylimidazolidine-2,4-dione (CAS 1266784-17-1)
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Recommended Standards
- Ethyl 6-bromo-3-fluoroimidazo[1,2-a]pyridine-2-carboxylate (CAS 2208822-59-5)
- Ethyl 7-bromo-4-fluoropyrazolo[1,5-a]pyridine-3-carboxylate (CAS 2387596-83-8)
- Ethyl 5-bromo-3-fluoroimidazo[1,2-a]pyridine-2-carboxylate (CAS 2170670-76-3)
- Ethyl 8-bromo-3-fluoroimidazo[1,2-a]pyridine-2-carboxylate (CAS 2306263-93-2)
- 6-Chloro-3-iodo-1-methyl-1H-pyrazolo[3,4-b]pyridine (CAS 1539296-59-7)
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