4-chloro-5-nitro-1,3-dihydropyrrolo[2,3-b]pyridin-2-one CAS 2306263-86-3
| CAS No. | 2306263-86-3 |
| Molecular Formula | C7H10ClN3O3 |
| Molecular Weight | 219.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-chloro-5-nitro-1,3-dihydropyrrolo[2,3-b]pyridin-2-one (CAS 2306263-86-3) is a high-purity analytical reference standard with the molecular formula C7H10ClN3O3 and a molecular weight of 219.63 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 4-chloro-5-nitro-1,3-dihydropyrrolo[2,3-b]pyridin-2-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 219.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 4-chloro-5-nitro-1,3-dihydropyrrolo[2,3-b]pyridin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H10ClN3O3 |
| Molecular Weight | 219.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related chloro Standards
- 8-Chloro-1H-pyrazolo[4,3-c]quinolin-3(2H)-one (CAS 1015605-31-8)
- 6-Chloro-1,2-dihydro-pyrazolo[4,3-c]quinolin-3-one (CAS 1015605-47-6)
- 4-Chloro-6-methoxycinnoline-3-carbonitrile (CAS 1239784-36-1)
- 6-Chloro-1H-pyrazolo[3,4-b][1,8]naphthyridin-3-amine (CAS 1335220-58-0)
- 1-Acetyl-5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile (CAS 1352395-53-9)
- 8-chloro-3-methyl-3H-[1,2,3]triazolo[4,5-g]quinazoline (CAS 1384081-59-7)
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Recommended Standards
- 4-Chloro-[1,2,4]triazolo[4,3-a]quinoxalin-1-amine (CAS 494206-13-2)
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- 4-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]benzonitrile (CAS 944906-75-6)
- 5-Amino-1-(4-chlorophenyl)-1H-1,2,3-triazole-4-carbonitrile (CAS 98592-51-9)
- 2-Thiomorpholinonicotinic acid (CAS 1042803-37-1)
- 2-(5-(tert-Butylthio)pyridin-2-yl)-1,2,3,4-tetrahydroisoquinoline (CAS 1355179-82-6)
- 3-fluoro-7-hydroxy-5-methoxy-4-methyl-chromen-2-one (CAS 2920243-41-8)
- 4-(4-(Bis(2-hydroxyethyl)amino)phenyl)butanoic acid (CAS 34677-78-6)
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- Semaglutide impurity 89 (CAS CATO-C4X-222689)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com