| CAS No. | 2306264-76-4 |
| Molecular Formula | C20H34F2N2O2 |
| Molecular Weight | 372.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 372.49 g/mol gives ethyl 2-(3-amino-1-benzhydryl-azetidin-3-yl)-2,2-difluoro-acetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
ethyl 2-(3-amino-1-benzhydryl-azetidin-3-yl)-2,2-difluoro-acetate (CAS 2306264-76-4) is a high-purity analytical reference standard with the molecular formula C20H34F2N2O2 and a molecular weight of 372.49 g/mol.
ethyl 2-(3-amino-1-benzhydryl-azetidin-3-yl)-2,2-difluoro-acetate (C20H34F2N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
| Molecular Formula | C20H34F2N2O2 |
| Molecular Weight | 372.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |