Tert-butyl 3-(methylamino)-3-(trifluoromethyl)piperidine-1-carboxylate CAS 2306268-66-4
| CAS No. | 2306268-66-4 |
| Molecular Formula | C12H21F3N2O2 |
| Molecular Weight | 282.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 282.30 g/mol gives Tert-butyl 3-(methylamino)-3-(trifluoromethyl)piperidine-1-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Tert-butyl 3-(methylamino)-3-(trifluoromethyl)piperidine-1-carboxylate (CAS 2306268-66-4), molecular formula C12H21F3N2O2 and molecular weight 282.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Tert-butyl 3-(methylamino)-3-(trifluoromethyl)piperidine-1-carboxylate (C12H21F3N2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Tert-butyl 3-(methylamino)-3-(trifluoromethyl)piperidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H21F3N2O2 |
| Molecular Weight | 282.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Tert-butyl (S)-4-(1-amino-2,2,2-trifluoroethyl)piperidine-1-carboxylate (CAS 2306244-99-3)
- Tert-butyl 4-(methylamino)-4-(trifluoromethyl)piperidine-1-carboxylate (CAS 2306276-40-2)
- Tert-butyl (R)-4-(1-amino-2,2,2-trifluoroethyl)piperidine-1-carboxylate (CAS 2306247-86-7)
- Tert-butyl methyl((3R,5R)-5-(trifluoromethyl)piperidin-3-yl)carbamate (CAS 2227198-04-9)
- 1-(3-Bromo-2-chloro-6-fluorophenyl)ethan-1-one (CAS 1704367-13-4)
- N-Methyl-N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]propan-2-amine (CAS 934586-46-6)
- tert-Butyl 4,6-dimethoxy-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate (CAS 1260773-19-0)
- (6ar)-2-methoxy-6-(prop-2-en-1-yl)-5,6,6a,7-tetrahydro-4h-dibenzo[de,g]quinolin-1-ol 41932-35-8 KST-1A4756 (CAS 41932-35-8)
- (2s)-2-Amino-N,N-dimethylpropanamide hydrochloride (CAS 125218-79-3)
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- 3-Bromo-2-difluoromethoxy-4-nitrotoluene (CAS 1805527-24-5)
- 3-Nitro-N-(2-phenylbenzo[d]oxazol-5-yl)benzamide (CAS 331447-57-5)
- 3-(Benzylamino)-2-(methylthio)-4-phenylthiazol-3-ium iodide (CAS 105701-08-4)
- FMRF-Like Neuropeptide (CAS 121801-61-4)
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