2-(6-Fluoropyridin-3-yl)pyrimidine-5-carboxylic acid CAS 2306270-19-7
| CAS No. | 2306270-19-7 |
| Molecular Formula | C10H6FN3O2 |
| Molecular Weight | 219.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(6-Fluoropyridin-3-yl)pyrimidine-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-(6-Fluoropyridin-3-yl)pyrimidine-5-carboxylic acid (CAS 2306270-19-7) is a high-purity analytical reference standard with the molecular formula C10H6FN3O2 and a molecular weight of 219.17 g/mol.
The molecular framework of 2-(6-Fluoropyridin-3-yl)pyrimidine-5-carboxylic acid (C10H6FN3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6FN3O2 |
| Molecular Weight | 219.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluoropyridin Standards
- 2-(5-Fluoropyridin-2-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine (CAS 1373223-58-5)
- 1-(6-Fluoropyridin-3-yl)-4-oxocyclohexane-1-carbonitrile (CAS 1600498-50-7)
- 1-(5-Fluoropyridin-2-yl)-4-oxocyclohexanecarbonitrile (CAS 960371-10-2)
- 1,2-Bis(2-fluoropyridin-4-yl)ethane (CAS 954097-21-3)
- (1-(2-Fluoropyridin-4-yl)-3-methyl-1H-pyrazol-4-yl)boronic acid (CAS 2225178-82-3)
- 3-(5-Fluoropyridin-3-yl)benzoic acid (CAS 1247805-05-5)
- 4-(3-Fluoropyridin-2-yl)benzoic acid (CAS 1260650-69-8)
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Recommended Standards
- (4-Amino-3-(difluoromethyl)phenyl)dimethylphosphine oxide (CAS 2903925-11-9)
- 2-Cyano-6-fluoro-5-methyl-3-oxo-3,4-dihydroquinoxalin-1-ium-1-olate (CAS 952587-05-2)
- 6-hydroxy-5-sulfopyridine-3-carboxylic acid (CAS 1443980-09-3)
- 2-Hydroxy-5-sulfonicotinic Acid (CAS 334708-05-3)
- PP 242 (CAS 1092351-67-1)
- 4-Isopropyl-1,5-dioxo-2,3,4,5-tetrahydropyrrolo[1,2-a]quinazoline-3a(1h)-carboxylic acid (CAS 848316-28-9)
- 6-Bromo-2,3-difluorobenzoyl chloride (CAS 1263376-72-2)
- 1-Ethyl-5-hydroxy-2-pyrrolidinone (CAS 72954-65-5)
- N-(4-(3,4-Dihydroisoquinolin-2(1H)-yl)but-2-yn-1-yl)-4-methylthiophene-2-carboxamide (CAS 1351596-47-8)
- 3-Methyl-4-(piperazin-1-yl)benzaldehyde (CAS 1407276-74-7)
- [1-(2-Amino-ethyl)-piperidin-3-ylmethyl]-benzyl-cyclopropyl-amine (CAS 1353987-91-3)
- (S)-2-Amino-3-methoxypropan-1-ol (CAS 148278-95-9)
- 5-Azaspiro[2.4]heptan-7-ol (CAS 944258-72-4)
- Semaglutide Impurity 163 (x TFA Salt) (CAS CATO-C4X-2226163)
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